GSK461364

目录号: A10442

PLK 抑制剂

GSK461364

GSK461364 Chemical Structure

CAS NO. 929095-18-1

GSK461364 是polo样激酶1 (Plk1)的ATP竞争性抑制剂。

库存: 现货

规格 价格 数量
5 mg
¥ 800.00
10 mg
¥ 1,500.00
25 mg
¥ 3,000.00
50 mg
¥ 4,800.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

GSK461364 是polo样激酶1 (Plk1)的ATP竞争性抑制剂。
靶点信息
PLK1 (Cell-free assay)
2.2 nM(Ki)
In vitro (25°C) DMSO 9 mg/mL (16.55 mM)
Water Insoluble
Ethanol 27 mg/mL (49.66 mM)
In vivo 1% DMSO+30% polyethylene glycol+1% Tween 80 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.4 mL 91.98 mL 183.96 mL
0.5 mM 3.68 mL 18.4 mL 36.79 mL
1 mM 1.84 mL 9.2 mL 18.4 mL
5 mM 0.37 mL 1.84 mL 3.68 mL

*The above data is based on the productmolecular weight 543.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10442
作用机制 Inhibitor (抑制剂)
M. Wt 543.6
Formula C27H28F3N5O2S
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 929095-18-1
Synonyms GSK 461364, GSK-461364
SMILES C[C@H](C1=CC=CC=C1C(F)(F)F)OC2=C(SC(=C2)N3C=NC4=C3C=C(C=C4)CN5CCN(CC5)C)C(=O)N

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