Guanfacine hydrochloride

Name: Guanfacine hydrochloride
SKU: A15098

目录号: A15098

α2A-adrenoceptor 激动剂

Guanfacine hydrochloride Chemical Structure

CAS NO. 29110-48-3

Guanfacine hydrochloride是一种抗高血压药，是一种选择性的α2A肾上腺素受体激动剂，Kd为31 nM，选择性是α2B肾上腺素受体的60倍。

库存：现货

规格	价格	数量
10 mg	￥ 500.00
50 mg	￥ 1,500.00
100 mg	￥ 2,900.00

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生物活性

Guanfacine hydrochloride是一种抗高血压药，是一种选择性的α2A肾上腺素受体激动剂，Kd为31 nM，选择性是α2B肾上腺素受体的60倍。

靶点信息

α2A-adrenoceptor

溶解度 *

In vitro	DMSO	48 mg/mL (169.88 mM)
	Water	26 mg/mL (92.01 mM)
	Ethanol	48 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	35.39 mL	176.96 mL	353.92 mL
0.5 mM	7.08 mL	35.39 mL	70.78 mL
1 mM	3.54 mL	17.7 mL	35.39 mL
5 mM	0.71 mL	3.54 mL	7.08 mL

*The above data is based on the productmolecular weight 282.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A15098
作用机制	Agonist (激动剂)
M. Wt	282.55
Formula	C9H10Cl3N3O
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	29110-48-3
Synonyms	Guanfacine, Tenex, Intuniv
SMILES	C1=CC(=C(C(=C1)Cl)CC(=O)N=C(N)N)Cl.Cl