GW3965 HCl

Name: GW3965 HCl
SKU: A11204

目录号: A11204

LXR-like receptors 激动剂

Product Citations (3)

GW3965 HCl Chemical Structure

CAS NO. 405911-17-3

GW3965 HCl是一种选择性的口服活性肝X受体（LXR）完全激动剂。

库存：现货

规格	价格	数量
5 mg	￥ 600.00
10 mg	￥ 1,000.00
50 mg	￥ 3,800.00
100 mg	￥ 6,600.00
10mM * 1mL in DMSO	￥ 800.00

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生物活性

GW3965 HCl是一种选择性的口服活性肝X受体（LXR）完全激动剂。

靶点信息

hLXRβ (Cell-free assay)	LXRα/SRC1?LiSA (Cell-free assay)	hLXRα (Cell-free assay)
30 nM(EC50)	125 nM(EC50)	190 nM(EC50)

溶解度 *

In vitro	DMSO	Warmed: 16 mg/mL (25.86 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	16.17 mL	80.84 mL	161.68 mL
0.5 mM	3.23 mL	16.17 mL	32.34 mL
1 mM	1.62 mL	8.08 mL	16.17 mL
5 mM	0.32 mL	1.62 mL	3.23 mL

*The above data is based on the productmolecular weight 618.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11204
作用机制	Agonist (激动剂)
M. Wt	618.51
Formula	C33H31ClF3NO3.HCl
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	405911-17-3
Synonyms	GW-3965
SMILES	C1=CC=C(C=C1)C(CN(CCCOC2=CC=CC(=C2)CC(=O)O)CC3=C(C(=CC=C3)C(F)(F)F)Cl)C4=CC=CC=C4.Cl