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H-1152 dihydrochloride是一种异喹啉磺酰胺衍生物，是Rho激酶的一种更特异，更强且可透过膜的抑制剂，Ki值为1.6 nM，但对其他丝氨酸/苏氨酸激酶的抑制作用较弱。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.49 mL | 127.44 mL | 254.88 mL |
| 0.5 mM | 5.1 mL | 25.49 mL | 50.98 mL |
| 1 mM | 2.55 mL | 12.74 mL | 25.49 mL |
| 5 mM | 0.51 mL | 2.55 mL | 5.1 mL |
*The above data is based on the productmolecular weight 392.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15102 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 392.34 |
| Formula | C16H23Cl2N3O2S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 871543-07-6 |
| Synonyms | H 1152 dihydrochloride, H1152 dihydrochloride |
| SMILES | CC1CNCCCN1S(=O)(=O)C2=CC=CC3=CN=CC(=C32)C.Cl.Cl |
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