HIF-2a Translation Inhibitor

目录号: A16181

HIF-2a translation 抑制剂

HIF-2a Translation Inhibitor

HIF-2a Translation Inhibitor Chemical Structure

CAS NO. 882268-69-1

HIF-2a Translation Inhibitor(IC50值为5 uM);独立于HIF-2a mRNA表达或HIF-2a蛋白稳定性,并独立于mTOR活性,降低常氧和低氧状态下HIF-2a蛋白和HIF-2a目标基因的表达。此外,翻译抑制剂76增强了IRP1与HIF-2a IRE(铁反应元件)的结合。

库存: 现货

规格 价格 数量
5 mg
¥ 700.00
10 mg
¥ 1,200.00
50 mg
¥ 4,800.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

HIF-2a Translation Inhibitor(IC50值为5 uM);独立于HIF-2a mRNA表达或HIF-2a蛋白稳定性,并独立于mTOR活性,降低常氧和低氧状态下HIF-2a蛋白和HIF-2a目标基因的表达。此外,翻译抑制剂76增强了IRP1与HIF-2a IRE(铁反应元件)的结合。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 34.81 mL 174.03 mL 348.06 mL
0.5 mM 6.96 mL 34.81 mL 69.61 mL
1 mM 3.48 mL 17.4 mL 34.81 mL
5 mM 0.7 mL 3.48 mL 6.96 mL

*The above data is based on the productmolecular weight 287.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A16181
作用机制 Inhibitor (抑制剂)
M. Wt 287.31
Formula C9H9N3O4S2
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 882268-69-1
SMILES COC(=O)C1=C(C=CS1)NN=C(C#N)S(=O)(=O)C

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