产品详情

生物活性

HMN-214抑制polo样和细胞周期蛋白依赖性激酶活性，具有强有力的抗微管作用，并在广泛的人类异种移植物中导致深度凋亡和抗肿瘤活性。

溶解度 *

In vitro (25°C)	DMSO	11 mg/mL (25.91 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	0.5% methylcellulose	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.56 mL	117.79 mL	235.57 mL
0.5 mM	4.71 mL	23.56 mL	47.11 mL
1 mM	2.36 mL	11.78 mL	23.56 mL
5 mM	0.47 mL	2.36 mL	4.71 mL

*The above data is based on the productmolecular weight 424.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10452
作用机制	Inhibitor (抑制剂)
M. Wt	424.5
Formula	C22H20N2O5S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	173529-46-9
Synonyms	IVX-214,HMN214
SMILES	CC(=O)N(C1=CC=CC=C1/C=C/C2=CC=[N+](C=C2)[O-])S(=O)(=O)C3=CC=C(C=C3)OC