Ibuprofen (Advil)

Name: Ibuprofen (Advil)
SKU: A10461

目录号: A10461

COX-1 抑制剂

Product Citations (2)

Ibuprofen (Advil) Chemical Structure

CAS NO. 15687-27-1

Ibuprofen (Advil)是一种非甾体抗炎药(NSAID)，靶向COX-1，IC50为13 μM。

库存：现货

规格	价格	数量
500 mg	￥ 450.00
10mM * 1mL in DMSO	￥ 590.00

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生物活性

Ibuprofen (Advil)是一种非甾体抗炎药(NSAID)，靶向COX-1，IC50为13 μM。

靶点信息

COX-1	COX-2
13 μM	370 μM

溶解度 *

In vitro (25°C)	DMSO	40 mg/mL (193.9 mM)
	Water	Insoluble
	Ethanol	40 mg/mL (193.9 mM)
In vivo	1% DMSO+30% polyethylene glycol+1% Tween 80	19 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	48.47 mL	242.37 mL	484.73 mL
0.5 mM	9.69 mL	48.47 mL	96.95 mL
1 mM	4.85 mL	24.24 mL	48.47 mL
5 mM	0.97 mL	4.85 mL	9.69 mL

*The above data is based on the productmolecular weight 206.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10461
作用机制	Inhibitor (抑制剂)
M. Wt	206.3
Formula	C13H18O2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	15687-27-1
Synonyms	Genpril, Brufen, Nurofen, Motrin, Ibren, Ibuprohm
SMILES	CC(C)CC1=CC=C(C=C1)C(C)C(=O)O