Immunology & Inflammation

产品 1 到 50 共 130个

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Catalog No. Product Name Application Product Information
A10881 SALE

Suplatast tosilate

Suplatast Tosilate is a novel capsular anti-asthmatic agent that suppresses both IgE production, IL-4 and IL-5 synthesis with IC50 above 100 μM.


IL-1 抑制剂
AS101, a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.


IL-12/23 抑制剂
APY0201 is a potent and selective IL-12/23 inhibitor.


interleukin-5 receptor 拮抗剂
YM-90709 is an interleukin-5 receptor antagonist. YM-90709 inhibits the binding of IL-5 to its receptor on peripheral human eosinophils and butyric acid-treated eosinophilic HL-60 clone 15 cells, with IC50 values of 1.0 and 0.57 microM, respectively.

IRAK-1-4 Inhibitor I

IRAK-1-4 inhibitor is a benzimidazole that disrupts the activity of IRAK-1 and -4 with IC50 values of 300 and 200 nM, respectively.
A13478 SALE

MCC950 sodium

NLRP3 抑制剂
MCC950 sodium is a potent NLRP3 inflammasome inhibitor that inhibits IL-1beta production with IC50 value of 7.5 nm.

beta-Interleukin I (163-171), human

T cell activator
beta-Interleukin I (163-171), human, a peptide. Interleukins are a group of cytokines (secreted proteins/signaling molecules) that were first seen to be expressed by white blood cells (leukocytes).
A11963 SALE


IL-17 抑制剂
Y320 is an orally active immunomodulator, and inhibits IL-17 production by CD4 T cells stimulated with IL-15 with IC50 of 20 to 60 nM.

SC 560

COX-1 抑制剂
SC 560 is a COX-1 selective inhibitor, which can be used as a pharmacological tool to study the role of COX-1-derived PGs in inflammation and pain.


COX 抑制剂
Xanthohumol, a prenylated chalcone from hop, inhibits COX-1 and COX-2 activity and shows chemopreventive effects.


COX-2 抑制剂
Etoricoxib specifically binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in inhibition of the conversion of arachidonic acid into prostaglandins. Inhibition of COX-2 may induce apoptosis and inhibit tumor cell proliferation and angiogenesis.


COX-1 抑制剂
Paradol is the active flavor constituent of the seeds of Guinea pepper (Aframomum melegueta); Paradol has been found to have antioxidative and antitumor promoting effects

Meclofenamate Sodium

COX 抑制剂
Meclofenamate Sodium is a dual COX-1/COX-2 inhibitor with IC50 of 40 nM and 50 nM.

ATB 346

COX-2 抑制剂
ATB-346 exhibits anti-inflammatory properties similar to naproxen, but with substantially reduced gastrointestinal toxicity.
A12043 SALE


COX-1 抑制剂
(-)-Epicatechin is a natural product from green tea. (-)Epicatechin is an inhibitor of Cox-1


COX 抑制剂
Pranoprofen is a non-steroidal anti-inflammatory drug used in ophthalmology


COX/5-LOX 抑制剂
Tepoxalin is a dual cyclooxygenase/5-lipoxygenase inhibitor of arachidonic acid metabolism with potent anti-inflammatory activity and a favorable gastrointestinal profile
A11859 SALE

Fexofenadine HCl

COX 抑制剂/histamine H1 receptor 激动剂
Fexofenadine HCl is an antihistamine that inhibits Cox-1, Cox-2, and is a histamine H1 receptor agonist


Hsp90/SRC/COX-2 抑制剂
Radicicol is a potent inhibitor of Hsp90, SRC, and Cox-2
A10030 SALE


COX 抑制剂

Bromfenac sodium

COX-2 抑制剂
Bromfenac sodium is a topically selective cyclooxygenase (COX)-2 inhibitor
A13116 SALE


COX-2 抑制剂?€?
A12434 SALE


COX 抑制剂
(S)-(+)-Flurbiprofen is a non-selective Cox-1 and Cox-2 inhibitor.

Iguratimod (T 614)

COX-2 抑制剂
Iguratimod(T 614) is one of a series of 4H-1-benzopyran-4-ones which has potent anti-inflammatory, analgesic and antipyretic activity. Iguratimod(T 614) is a selective inhibitor of cyclo-oxygenase-2 (COX-2), and inhibits the production of interleukin-1 (IL-1), IL-6, IL-8 and tumour necrosis factor.
A10736 SALE

Piroxicam (Feldene)

COX 抑制剂
Piroxicam is an effective and potent inhibitor of prostaglandin synthesis and a Cox-1 and Cox-2 inhibitor.
A10623 SALE

Naproxen sodium

COX 抑制剂
Naproxen sodium is a non-selective cyclooxygenase (COX) inhibitor that displays anti-inflammatory, antipyretic and analgesic effects. Has a neuroprotective role against colchicine-induced cognitive impairment and oxidative stress.
A13332 SALE

FK 3311

COX-2 抑制剂
FK3311 is a cell-permeable and orally available sulfonanilide that acts as a selective COX-2 inhibitor and NSAID.


COX-2 抑制剂
A13572 SALE


COX-2 抑制剂
Parecoxib is a potent and selective COX-2 inhibitor.


Fenbufen is an orally active phenylalkanoic derivative with anti-inflammatory, analgesic and antipyretic activity.


COX 抑制剂
Diflunisal is a salicylic acid derivative with analgesic and anti-inflammatory activity.

Amfenac Sodium Monohydrate

COX 抑制剂
Amfenac Sodium monohydrate is a non-steroidal analgesic anti-inflammatory drug with acetic acid moiety. The IC50 values for COX1 and COX2 is 250 nM and 150 nM, respectively.


COX 抑制剂
Ampiroxicam is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory drug.


COX-2 抑制剂
Carprofen reduces inflammation by inhibition of COX-2 and other sources of inflammatory prostaglandins, does not interfere with COX-1 activity.
A10720 SALE

Phenylbutazone (Butazolidin, Butatron)

COX 抑制剂
Phenylbutazone is a compound of research interest as an anti-inflammatory and anti-proliferative agent.
A10474 SALE

Indomethacin (Indocid, Indocin)

COX 抑制剂
Indomethacin is a nonselective COX1 and COX2 inhibitor with IC50 of 0.1 μg/mL and 5 μg/mL, respectively. Indomethacin(Indocid, Indocin) is a non-steroidal anti-inflammatory compound commonly used to reduce fever, pain, stiffness, and swelling.
A11906 SALE


Phenacetin is a non-opioid analgesic without anti-inflammatory properties.
A10461 SALE

Ibuprofen (Advil)

COX-1 抑制剂
Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) targeting COX-1 with an IC50 of 13 μM.

Ibuprofen Lysine (NeoProfen)

COX-1 抑制剂
Ibuprofen Lysine(Motrin) is a non-steroidal anti-inflammatory drug.

Asaraldehyde (Asaronaldehyde)

COX-2 抑制剂
Asaraldehyde is a selective COX-2 inhibitor.
A10193 SALE


COX-2 抑制剂

Celecoxib is a sulfa non-steroidal anti-inflammatory drug (NSAID) and selective COX-2 inhibitor used in the treatment of osteoarthritis, rheumatoid arthritis, acute pain, painful menstruation and menstrual symptoms, and to reduce numbers of colon and rectum polyps in patients with familial adenomatous polyposis.


Pravadoline (WIN 48098)

COX 抑制剂
Pravadoline (WIN 48,098) is antiinflammatory and prostaglandin synthesis inhibitor, acting through inhibition of the enzyme cyclooxygenase (COX).

Sulindac (Clinoril)

COX 抑制剂
Sulindac is a non-steroidal COX inhibitor, which potently inhibits prostaglandin synthesis, used in the treatment of acute or chronic inflammatory conditions
A11686 SALE

Flunixin meglumine

COX 抑制剂
Flunixin Meglumin is a potent inhibitor of the enzyme cyclooxygenase (COX) used as analgesic agent with anti-inflammatory and antipyretic activity.
A11692 SALE

Acemetacin (Emflex)

COX 抑制剂
Acemetacin is a glycolic acid ester of indometacin. It is metabolized to indometacin, which then acts as an inhibitor of cyclooxygenase, producing the anti-inflammatory effects.
A11693 SALE

Tolfenamic acid

COX-2 抑制剂
Tolfenamic Acid is a COX-2 inhibitor with IC50 of 0.2 μM. It is one of the class of non-steroidal anti-inflammatory drugs (NSAIDs). It is used to treat the symptoms of migraine.
A11918 SALE

Rofecoxib (Vioxx)

COX-2 抑制剂
Rofecoxib (Vioxx) is a?COX-2?inhibitor with?IC5N/A?of 18 nM.


ATB-337 is a hybrid molecule of an H2S donor and the NSAID diclofenac

Diclofenac sodium

COX 抑制剂
Diclofenac Sodium is a non-selective COX inhibitor with IC50 of 0.5 μg/ml and 0.5 μg/ml for COX-1 and -2 in intact cells, respectively, used as a nonsteroidal anti-inflammatory drug (NSAID) to relieve pain and reduce swelling in flammation.
A11697 SALE


Licofelone is a dual COX/LOX inhibitor, being considered as a treatment for osteoarthritis. It may reduce the gastrointestinal toxicity associated with other non-steroidal anti-inflammatory drugs, which only inhibit COX (cyclooxygenase). Licofelone is the first drug to inhibit both.

产品 1 到 50 共 130个

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