Irbesartan (Avapro)

Name: Irbesartan (Avapro)
SKU: A10477

目录号: A10477

AT1 拮抗剂

Irbesartan (Avapro) Chemical Structure

CAS NO. 138402-11-6

Irbesartan (Avapro)是一种血管紧张素II受体拮抗剂，IC50为1.3 nM，主要用于治疗高血压。

库存：现货

规格	价格	数量
10 mg	￥ 450.00
50 mg	￥ 950.00
100 mg	￥ 1,600.00

或

添加到收藏

产品仅用于科学研究，不针对患者销售，望谅解.

产品详情

生物活性

Irbesartan (Avapro)是一种血管紧张素II受体拮抗剂，IC50为1.3 nM，主要用于治疗高血压。

靶点信息

AT1 receptor
1.3 nM

溶解度 *

In vitro (25°C)	DMSO	Warmed: 3 mg/mL (7 mM)
	Water	Insoluble
	Ethanol	3 mg/mL (7 mM)
In vivo	30% PEG400+0.5% Tween80+5% propylene glycol	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.34 mL	116.69 mL	233.37 mL
0.5 mM	4.67 mL	23.34 mL	46.67 mL
1 mM	2.33 mL	11.67 mL	23.34 mL
5 mM	0.47 mL	2.33 mL	4.67 mL

*The above data is based on the productmolecular weight 428.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10477
作用机制	Antagonist (拮抗剂)
M. Wt	428.5
Formula	C25H28N6O
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	138402-11-6
Synonyms	BMS-186295, SR-47436, Aprovel, Karvea, BMS186295
SMILES	CCCCC1=NC2(CCCC2)C(=O)N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5