Ixabepilone

Name: Ixabepilone
SKU: A11449

目录号: A11449

microtubule 抑制剂

Product Citations (3)

Ixabepilone Chemical Structure

CAS NO. 219989-84-1

Ixabepilone是epothilone B类似物。

库存：现货

规格	价格	数量
5 mg	￥ 2,500.00
10 mg	￥ 4,200.00
25 mg	￥ 8,400.00
50 mg	￥ 14,500.00

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产品详情

生物活性

Ixabepilone是epothilone B类似物。

靶点信息

microtubule(tubulin stabilising)

溶解度 *

In vitro (25°C)	DMSO	95 mg/mL (187.48 mM)
	Water	Insoluble
	Ethanol	95 mg/mL (187.48 mM)
In vivo	2% DMSO+30% PEG 300+2% Tween 80+ddH2O	6 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.74 mL	98.68 mL	197.36 mL
0.5 mM	3.95 mL	19.74 mL	39.47 mL
1 mM	1.97 mL	9.87 mL	19.74 mL
5 mM	0.39 mL	1.97 mL	3.95 mL

*The above data is based on the productmolecular weight 506.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11449
作用机制	Inhibitor (抑制剂)
M. Wt	506.7
Formula	C27H42N2O5S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	219989-84-1
Synonyms	BMS-24755, Azaepothilone , BMS 247550-1
SMILES	C[C@H]1CCC[C@@]2([C@@H](O2)C[C@H](NC(=O)C[C@@H](C(C(=O)[C@@H]([C@H]1O)C)(C)C)O)/C(=C/C3=CSC(=N3)C)/C)C