JTT-705 (Dalcetrapib)

Name: JTT-705 (Dalcetrapib)
SKU: A11213

目录号: A11213

CETP 抑制剂

JTT-705 (Dalcetrapib) Chemical Structure

CAS NO. 211513-37-0

JTT-705 (Dalcetrapib)是一种CETP抑制剂，抑制CETP是增加HDL-胆固醇并可能减少动脉粥样硬化的目标。

库存：现货

规格	价格	数量
5 mg	￥ 1,500.00
10 mg	￥ 2,500.00
25 mg	￥ 4,800.00
50 mg	￥ 7,800.00
10mM * 1mL in DMSO	￥ 1,760.00

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生物活性

JTT-705 (Dalcetrapib)是一种CETP抑制剂，抑制CETP是增加HDL-胆固醇并可能减少动脉粥样硬化的目标。

靶点信息

rhCETP
0.2 μM

溶解度 *

In vitro (25°C)	DMSO	66 mg/mL (169.41 mM)
	Water	Insoluble
	Ethanol	66 mg/mL (169.41 mM)
In vivo	0.5% methylcellulose	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.67 mL	128.34 mL	256.67 mL
0.5 mM	5.13 mL	25.67 mL	51.33 mL
1 mM	2.57 mL	12.83 mL	25.67 mL
5 mM	0.51 mL	2.57 mL	5.13 mL

*The above data is based on the productmolecular weight 389.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11213
作用机制	Inhibitor (抑制剂)
M. Wt	389.6
Formula	C23H35NO2S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	211513-37-0
Synonyms	JTT705
SMILES	CCC(CC)CC1(CCCCC1)C(=O)NC2=CC=CC=C2SC(=O)C(C)C