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  1. KN-93 phosphate

    Catalog No. A22229
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    membrane-permeant synthetic inhibitor
    KN-93 phosphate is a novel membrane-permeant synthetic inhibitor of purified neuronal CaMK-II, with Ki of 370 nM. 了解更多
  2. NSC 80538

    Catalog No. A22655
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    NSC 80538 (1-(4-Chlorophenyl)-3-(4-fluorophenyl)thiourea) is an inhibitor of MEK Kinase PB1 Domains in Multiplex HTS Assay. 了解更多
  3. NSC 191412

    Catalog No. A22657
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    NSC 191412 (1-(4-Fluorophenyl)-3-phenylthiourea) is an active compound. 了解更多
  4. (-)-Ibuprofenamide

    Catalog No. A19398
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    (-)-Ibuprofenamide is an amide prodrug of Ibuprofen with anti-inflammatory activity. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively. 了解更多
  5. FCCP

    Catalog No. A16545
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    ionophore
    FCCP是一种离子载体,是一种可移动的离子载体。它是线粒体中氧化磷酸化的有效解偶联剂,可通过跨细胞膜转运质子来破坏ATP合成。 了解更多
  6. KN-92 phosphate

    Catalog No. A15139
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    CaMKII 抑制剂
    KN-92 phosphate是KN-93的非活性衍生物。KN-93是Ca2+/钙调蛋白依赖性激酶II(CaMKII)的选择性抑制剂,竞争性阻断CaM与激酶的结合(Ki = 370 nM)。 了解更多
  7. KN-92

    Catalog No. A15137
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    CaMK-II 抑制剂
    KN-92是KN-93的非活性衍生物。KN-93是Ca2+/钙调蛋白依赖性激酶II(CaMKII)的选择性抑制剂,竞争性阻断CaM与激酶的结合(Ki = 370 nM)。 了解更多
  8. Mosapride citrate

    Catalog No. A10607
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    5-HT4-receptor 激动剂
    Mosapride citrate起5-HT4受体激动剂和5-HT3受体拮抗剂的作用。 了解更多
  9. Avelumab

    Catalog No. A18234
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    PD-1/PD-L1
    Avelumab is a fully human IgG1 anti-PD-L1 monoclonal antibody with potential antibody-dependent cell-mediated cytotoxicity. 了解更多
  10. RY785

    Catalog No. A22104
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    inhibitor of Kv2.1 and Kv2.2
    RY785 (Kv2-IN-A1) is an inhibitor of Kv2.1 and Kv2.2. 了解更多
  11. PS210

    Catalog No. A22109
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    protein kinase PDK1 inhibitor
    PS210 is a substrate-selective protein kinase PDK1 inhibitor that acts by binding to the PIF-pocket allosteric docking site. 了解更多
  12. RH01687

    Catalog No. A22110
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    β-cell protector
    RH01687 is a potent β-cell protector that exhibits β-cell-protective activities against endoplasmic reticulum (ER) stress. 了解更多
  13. PythiDC

    Catalog No. A22127
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    inhibitor of collagen prolyl 4-hydroxylase
    PythiDC is a selective inhibitor of collagen prolyl 4-hydroxylase. 了解更多
  14. (Z)-JIB-04

    Catalog No. A22137
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    Jumonji histone demethylase inihibitor
    Z-JIB-04 (NSC 693627, JIB-04 Z-isomer) is an isomer of JIB-04. JIB-04 is a pan-selective Jumonji histone demethylase inihibitor with IC50 of 230 nM, 340 nM, 855 nM, 445 nM, 435 nM, 1100 nM and 290 nM for JARID1A, JMJD2E, JMJD3, JMJD2A, JMJD2B, JMJD2C, and JMJD2D, respectively. 了解更多
  15. Molnupiravir

    Catalog No. A22165
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    broad-spectrum antiviral activity
    Molnupiravir (EIDD-2801, MK-4482) is an orally bioavailable prodrug of the ribonucleoside analog β-d-N4-hydroxycytidine (NHC; EIDD-1931) with broad-spectrum antiviral activity against SARS-CoV-2, MERS-CoV, SARS-CoV, and the causative agent of COVID-19. 了解更多
  16. TSPC (HUN86320)

    Catalog No. A22250
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    inhibitor for GA perception
    TSPC is an inhibitor for GA perception by in vitro and in planta evaluations. 了解更多
  17. PF-562271 hydrochloride

    Catalog No. A22370
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    FAK and Pyk2 kinase inhibitor
    PF-562271 hydrochloride is a potent, ATP-competitive and reversible FAK and Pyk2 kinase inhibitor with IC50s of 1.5 nM and 13 nM, respectively. 了解更多
  18. Gambogenic acid

    Catalog No. A22383
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    EZH2 inhibitor
    Gambogenic acid is an active ingredient in gamboge, with anticancer activity. Gambogenic acid acts as an effective inhibitor of EZH2, specifically and covalently binds to Cys668 within the EZH2-SET domain, and induces EZH2 ubiquitination. 了解更多
  19. TM5007

    Catalog No. A22710
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    PAI-1 inhibitor
    TM5007 is a poent inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 29 uM. 了解更多
  20. CV-159

    Catalog No. A20731
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    dihydropyridine Ca2+ antagonist
    CV-159 is a unique dihydropyridine Ca2+ antagonist with an anti-calmodulin (CaM) action, and has antiinflammatory activities. 了解更多
  21. NKL 22

    Catalog No. A20600
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    HDAC inhibitor
    NKL 22 is a HDAC inhibitor. The value of IC 50 is 78 uM NKL 22 increase frataxin protein concentrations NKL 22 inhibitors increase FXN mRNA in FRDA lymphocytes. HDAC inhibitors act directly on FXN. 了解更多
  22. CFMTI

    Catalog No. A20567
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    mGluR 1 allosteric antagonist
    CFMTI is a potent and selective metabotropic glutamate receptor (mGluR) 1 allosteric antagonist with IC50 of 2.6 nM. 了解更多
  23. WT-161

    Catalog No. A20432
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    HDAC6 inhibitor
    WT-161 is a potent and selective HDAC6 inhibitor with an IC50 of 0.40 nM. 了解更多
  24. RMI 10874

    Catalog No. A20370
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    RMI 10874 is a tilorone analogue. Tilorone is a small-molecule, orally bioavailable antiviral agent. RMI 10874 completely abolishes lung colonization of an H-2 negative (GR9.B9) MCA-induced fibrosarcoma clone. 了解更多
  25. 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide

    Catalog No. A20334
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    2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide is a compound that inhibits stress-induced ulcer and low toxicity, and can maintain the content of phospholipase A2 and prostaglandin E2 in ulcerated rats induced by water immersed restrained stress. 了解更多
  26. ABT-072

    Catalog No. A20177
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    NS5B polymerase inhibitor
    ABT-072 is a nonnucleoside NS5B polymerase inhibitor and a candidate drug evaluated for treatment of hepatitis C virus. 了解更多
  27. CE3F4

    Catalog No. A20067
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    Epac1 antagonist
    CE3F4 is a selective antagonist of exchange protein directly activated by cAMP (Epac1), with IC50s of 10.7 μM and 66 μM for Epac1 and Epac2(B), respectively. 了解更多
  28. YK11

    Catalog No. A20033
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    Androgen receptor partial agonist
    YK11 is a partial agonist of androgen receptor, with osteogenic activity. 了解更多
  29. Tubulin inhibitor 1

    Catalog No. A19998
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    tubulin inhibitor
    Tubulin inhibitor 1 is a tubulin inhibitor, inhibits tubulin polymerization. 了解更多
  30. PF 03709270

    Catalog No. A19948
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    PF 03709270 is an orally available ester prodrug form of sulopenem, with broad-spectrum antibacterial activity against most gram-positive and gram-negative bacteria. 了解更多
  31. CG-806

    Catalog No. A19814
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    FLT3/BTK inhibitor
    CG-806 is an orally active, potent and non-covalent pan-FLT3/pan-BTK inhibitor with an IC50 of 0.08 μM for FLT3. CG-806 has an IC50 of 11 nM against FLT3 wild type (WT)-transfected Ba/F3 cells. 了解更多
  32. Diethyl-pythiDC

    Catalog No. A19766
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    CP4Hs inhibitor
    Diethyl-pythiDC is an inhibitor of collagen prolyl 4-hydroxylases (CP4Hs). 了解更多
  33. BI-882370

    Catalog No. A19734
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    RAF inhibitor
    BI-882370 is a potent and selective RAF kinase inhibitor that binds to the ATP binding site of the kinase positioned in the DFG-out (inactive) conformation of the BRAF kinase. 了解更多
  34. Ensartinib

    Catalog No. A19720
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    ALK/MET inhibitor
    Ensartinib (X-396) is a potent and dual ALK/MET inhibitor with IC50s of <0.4 nM and 0.74 nM, respectively. 了解更多
  35. RO-7

    Catalog No. A19695
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    PA endonuclease inhibitor
    RO-7 is a next-generation polymerase (PA) endonuclease inhibitor of influenza A and B viruses. 了解更多
  36. CA-5f

    Catalog No. A19668
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    macroautophagy/autophagy inhibitor
    CA-5f is a potent late-stage macroautophagy/autophagy inhibitor via inhibiting autophagosome-lysosome fusion. 了解更多
  37. GlyRS-IN-1

    Catalog No. A19543
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    GlyRS inhibitor
    GlyRS-IN-1 is a glycyl-tRNA synthase (GlyRS) inhibitor extracted from patent WO 2017066459 A1. GlyRS-IN-1 can also inhibit the growth of bacteria. 了解更多
  38. FDI-6

    Catalog No. A19514
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    FOXM1 inhibitor
    FDI-6 is an inhibitor of FOXM1. FDI-6 binds directly to FOXM1 protein, to displace FOXM1 from genomic targets in MCF-7 breast cancer cells, and induce concomitant transcriptional down-regulation. 了解更多
  39. GDC-0077

    Catalog No. A19494
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    PI3Kα inhibitor
    GDC-0077 (RG6114) is a potent, orally available, and selective PI3Kα inhibitor (IC50=0.038 nM). 了解更多
  40. Acetylazide

    Catalog No. A19370
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    Acetylazide is a synthetic broad-spectrum bacteriostatic antibiotic. 了解更多
  41. BB-Cl-Amidine

    Catalog No. A19265
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    PAD inhibitor
    BB-Cl-Amidine is a peptidylarginine deminase (PAD) inhibitor. 了解更多
  42. Ionomycin calcium

    Catalog No. A21370
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    Ionomycin calcium (SQ23377 calcium) is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. 了解更多
  43. Fexinidazole

    Catalog No. A21274
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    Fexinidazole is a 5-nitroimidazole drug currently in clinical development for the treatment of human sleeping sickness (human African trypanosomiasis [HAT]), caused by infection with species of the protozoan parasite Trypanosoma brucei. 了解更多
  44. Goserelin

    Catalog No. A21197
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    GnRH agonist
    Goserelin(ICI 118630) is an injectable gonadotropin releasing hormone superagonist (GnRH agonist). 了解更多
  45. MSI-1436 lactate

    Catalog No. A21929
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    PTB1B inhibitor
    MSI-1436 lactate is a selective, non-competitive inhibitor of the enzyme protein-tyrosine phosphatase 1B (PTB1B), with an IC50 of 1 μM, 200-fold preference over TCPTP (IC50 of 224 μM). 了解更多
  46. Liarozole dihydrochloride

    Catalog No. A21853
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    CYP450 dependent inhibitor
    Liarozole dihydrochloride (R75251; R85246) is a cytochrome P450 (CYP450) dependent inhibitor, orally active, it also a potent inhibitor of estrogen (via inhibition of aromatase) and testicular androgen synthesis (inhibition of 17 ,20-lyase). 了解更多
  47. Ensartinib hydrochloride

    Catalog No. A21719
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    ALK/MET inhibitor
    Ensartinib hydrochloride (X-396 hydrochloride) is a potent and dual ALK/MET inhibitor with IC50s of <0.4 nM and 0.74 nM, respectively. 了解更多
  48. 5-Hydroxy Propafenone D5 Hydrochloride

    Catalog No. A21604
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    5-Hydroxy Propafenone D5 Hcl is the deuterium labeled 5-Hydroxy Propafenone. 了解更多
  49. YS-49

    Catalog No. A21198
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    PI3K/Akt activator
    YS-49 is a PI3K/Akt (a downstream target of RhoA) activator, to reduce RhoA/PTEN activation in the 3-methylcholanthrene-treated cells. 了解更多
  50. Arhalofenate

    Catalog No. A21135
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    PPARγ agonist
    Arhalofenate (MBX 102) is a selective partial agonist of peroxisome proliferator-activated receptor (PPAR)-γ, used for the treatment of type 2 diabetes. 了解更多

产品 1 到 50 共 161个

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