微信关注
Total item
Cart Subtotal
￥ 0.00 产品详情
ki8751是一种细胞可渗透的喹啉氧基苯基脲化合物，在基于细胞和无细胞的检测中起Flk-1 (VEGFR-2)选择性抑制剂的作用。
Targets
| Target | Value |
|---|---|
| VEGFR2 | IC50: 0.9nM |
| c-Kit | IC50: 40nM |
| PDGFRα | IC50: 67nM |
| FGFR2 | IC50: 170nM |
| EGFR | IC50: >10μM |
| HGFR | IC50: >10μM |
| Insulin Receptor | IC50: >10μM |
| In vitro (25°C) | DMSO | 46 mg/mL (97.99 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 4% DMSO+corn oil | 2.3 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.3 mL | 106.52 mL | 213.04 mL |
| 0.5 mM | 4.26 mL | 21.3 mL | 42.61 mL |
| 1 mM | 2.13 mL | 10.65 mL | 21.3 mL |
| 5 mM | 0.43 mL | 2.13 mL | 4.26 mL |
*The above data is based on the productmolecular weight 469.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10502 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 469.4 |
| Formula | C24H18F3N3O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 228559-41-9 |
| Synonyms | Ki-8751 |
| SMILES | COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC(=C(C=C3)NC(=O)NC4=C(C=C(C=C4)F)F)F |
产品标签
Product Questions
Product Questions
No Questions
您还可能对下列产品感兴趣
XL647 (Tesevatinib)
XL647 (Tesevatinib)是一种口服生物可利用的小分子RTK抑制剂，可结合并抑制在肿瘤细胞增殖和肿瘤血管形成中…
(-)-Catechin gallate
(-)-Catechin gallate是绿茶的抗氧化成分。在uM浓度下，抑制VEGF诱导的酪氨酸磷酸化。
Cediranib (AZD2171)
Cediranib (AZD2171)是一种高效的VEGFR(KDR)抑制剂，此外对c-Kit和PDGFRβ也具有相似的抑制活性，对VEGFR的选择性比P…
Kaempferol
Kaempferol被发现抑制Ki为0.3-0.5 μM的牛主动脉肌球蛋白轻链激酶，并且还被发现通过新的ERK-NFκB-cMyc-p21途径抑…
ZM 323881 hydrochloride
ZM 323881 hydrochloride是一种有效且选择性的人血管内皮生长因子受体2（VEGFR2/KDR）激酶活性抑制剂。
BMS-817378
BMS-817378是Met/VEGFR-2双重抑制剂BMS-794833的新型前药。
Keywords:购买 Ki8751 | Ki8751 供应商 | 订购 Ki8751 | Ki8751 价格 | Ki8751 生产商 | 订单 Ki8751 | Ki8751 代理商 | 购买 228559-41-9| 228559-41-9 供应商 | 订购 228559-41-9 | 228559-41-9 价格 | 228559-41-9 生产商 | 订单 228559-41-9 | 228559-41-9 代理商|buy Ki8751 | Ki8751 Supplier | purchase Ki8751 | Ki8751 cost | Ki8751 manufacturer | order Ki8751 | Ki8751 distributor | buy 228559-41-9| 228559-41-9 Supplier | purchase 228559-41-9 | 228559-41-9 cost | 228559-41-9 manufacturer | order 228559-41-9 | 228559-41-9 distributor