KN-93 Phosphate

Name: KN-93 Phosphate
SKU: A14288

目录号: A14288

CaMKII 抑制剂

Product Citations (1)

KN-93 Phosphate Chemical Structure

CAS NO. 1188890-41-6

KN-93 Phosphate是一种有效且特异性的Ca2+/钙调蛋白依赖性蛋白激酶II（CaMKII）抑制剂，Ki为0.37μM，对APK，PKC，MLCK或Ca2+-PDE活性无明显抑制作用。

库存：现货

规格	价格	数量
10 mg	￥ 1,100.00
25 mg	￥ 2,200.00
50 mg	￥ 4,000.00
10mM * 1mL in DMSO	￥ 1,250.00

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生物活性

KN-93 Phosphate是一种有效且特异性的Ca2+/钙调蛋白依赖性蛋白激酶II（CaMKII）抑制剂，Ki为0.37μM，对APK，PKC，MLCK或Ca2+-PDE活性无明显抑制作用。

靶点信息

CaMKII
0.37 μM(Ki)

溶解度 *

In vitro	DMSO	86 mg/mL (143.56 mM)
	Water	79 mg/mL (131.88 mM)
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	16.69 mL	83.47 mL	166.94 mL
0.5 mM	3.34 mL	16.69 mL	33.39 mL
1 mM	1.67 mL	8.35 mL	16.69 mL
5 mM	0.33 mL	1.67 mL	3.34 mL

*The above data is based on the productmolecular weight 599.03. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A14288
作用机制	Inhibitor (抑制剂)
M. Wt	599.03
Formula	C26H29ClN2O4S. H3O4P
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1188890-41-6
Synonyms	KN93, KN 93
SMILES	[HH].CN(C/C=C/C1=CC=C(C=C1)Cl)CC2=CC=CC=C2N(CCO)S(=O)(=O)C3=CC=C(C=C3)OC.OOP(=O)=O