KPT 335 | SINE 抑制剂 | 美国进口 | KPT 335 供应商 AdooQ®

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Cell Metabolism /
CRM1 /
KPT 335

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产品详情

生物活性

KPT 335是口服可生物利用的核出口选择性抑制剂（SINE）。

靶点信息

CRM1

溶解度 *

In vitro (25°C)	DMSO	83 mg/mL (187.65 mM)
	Water	Insoluble
	Ethanol	Warmed: 10 mg/mL
In vivo	5% DMSO+corn oil	14 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.61 mL	113.04 mL	226.08 mL
0.5 mM	4.52 mL	22.61 mL	45.22 mL
1 mM	2.26 mL	11.3 mL	22.61 mL
5 mM	0.45 mL	2.26 mL	4.52 mL

*The above data is based on the productmolecular weight 442.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A16078
作用机制	Inhibitor (抑制剂)
M. Wt	442.32
Formula	C18H12F6N6O
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1392136-43-4
Synonyms	Verdinexor
SMILES	O=C(NNC1=NC=CC=C1)/C=C\N2N=C(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)N=C2

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产品资料

Download KPT 335 SD file

Products Specification Data Sheet

Safety Data Sheet (SDS)

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