LCZ696 (Valsartan)

目录号: A14206

angiotensin receptor-neprilysin 抑制剂

LCZ696 (Valsartan)

LCZ696 (Valsartan) Chemical Structure

CAS NO. 936623-90-4

LCZ696 (Valsartan)是一种生物利用型双效血管紧张素受体-中性溶血素抑制剂(ARNi),用于治疗高血压和心力衰竭。

库存: 现货

规格 价格 数量
5 mg
¥ 650.00
10 mg
¥ 900.00
25 mg
¥ 1,800.00
10mM * 1mL in DMSO
¥ 1,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

LCZ696 (Valsartan)是一种生物利用型双效血管紧张素受体-中性溶血素抑制剂(ARNi),用于治疗高血压和心力衰竭。
靶点信息
RAAS
In vitro DMSO Warmed: 26 mg/mL (28.38 mM)
Water Warmed: 88 mg/mL (96.07 mM)
Ethanol Warmed: 8 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 10.92 mL 54.59 mL 109.17 mL
0.5 mM 2.18 mL 10.92 mL 21.83 mL
1 mM 1.09 mL 5.46 mL 10.92 mL
5 mM 0.22 mL 1.09 mL 2.18 mL

*The above data is based on the productmolecular weight 915.98. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A14206
作用机制 Inhibitor (抑制剂)
M. Wt 915.98
Formula C24H29N5O3.C24H29NO5.5/2H2O.3Na
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 936623-90-4
Synonyms LCZ 696, LCZ-696
SMILES CCCCC(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)[C@@H](C(C)C)C(=O)O.CCOC(=O)[C@H](C)C[C@@H](CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)CCC(=O)O.O.O.O.[Na+].[Na+].[Na+]

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