Loratadine

目录号: A10538

Loratadine

Loratadine Chemical Structure

CAS NO. 79794-75-5

Loratadine是一种非镇静抗组胺药,抑制组胺诱导的内皮细胞分泌IL-6和IL-8的活性。氯雷他定是一种选择性外周组胺h1受体拮抗剂,IC50 > 32 μM。

库存: 现货

规格 价格 数量
10 mg
¥ 450.00
25 mg
¥ 800.00
50 mg
¥ 1,200.00
100 mg
¥ 1,900.00
10mM * 1mL in DMSO
¥ 550.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Loratadine是一种非镇静抗组胺药,抑制组胺诱导的内皮细胞分泌IL-6和IL-8的活性。氯雷他定是一种选择性外周组胺h1受体拮抗剂,IC50 > 32 μM。
靶点信息
H1 receptor B(0)AT2
N/A4 μM
In vitro DMSO 15 mg/mL (39.18 mM)
Water Insoluble
Ethanol 68 mg/mL (177.6 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.15 mL 130.76 mL 261.51 mL
0.5 mM 5.23 mL 26.15 mL 52.3 mL
1 mM 2.62 mL 13.08 mL 26.15 mL
5 mM 0.52 mL 2.62 mL 5.23 mL

*The above data is based on the productmolecular weight 382.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10538
M. Wt 382.39
Formula C22H23ClN2O2
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 79794-75-5
Synonyms Alavert, Claritin
SMILES CCOC(=O)N1CCC(=C2C3=C(CCC4=C2N=CC=C4)C=C(C=C3)Cl)CC1

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