LOXO-101 sulfate

目录号: A16239

TRK 抑制剂

LOXO-101 sulfate

LOXO-101 sulfate Chemical Structure

CAS NO. 1223405-08-0

LOXO-101 sulfate是一种小分子,设计用于阻断TRK家族的ATP结合位点,对TRKA,TRKB和TRKC激酶具有2至20 nM的细胞效力。

库存: 现货

规格 价格 数量
5 mg
¥ 550.00
10 mg
¥ 900.00
50 mg
¥ 1,800.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

LOXO-101 sulfate是一种小分子,设计用于阻断TRK家族的ATP结合位点,对TRKA,TRKB和TRKC激酶具有2至20 nM的细胞效力。
靶点信息
TRK
In vitro DMSO 88 mg/mL (167.13 mM)
Water Insoluble
Ethanol 88 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.99 mL 94.96 mL 189.93 mL
0.5 mM 3.8 mL 18.99 mL 37.99 mL
1 mM 1.9 mL 9.5 mL 18.99 mL
5 mM 0.38 mL 1.9 mL 3.8 mL

*The above data is based on the productmolecular weight 526.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A16239
作用机制 Inhibitor (抑制剂)
M. Wt 526.51
Formula C21H24F2N6O6S
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1223405-08-0
Synonyms LOXO101 sulfate, LOXO 101 sulfate
SMILES C1CC(N(C1)C2=NC3=C(C=NN3C=C2)NC(=O)N4CCC(C4)O)C5=C(C=CC(=C5)F)F.OS(=O)(=O)O

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