LY2109761

目录号: A11133

TβRI/II kinase 抑制剂

LY2109761

LY2109761 Chemical Structure

CAS NO. 700874-71-1

LY2109761是一种新型的I型和II型转化生长因子β受体双重抑制剂,对Smad2的磷酸化产生负面影响,作为抑制胰腺癌转移的治疗方法。

库存: 现货

规格 价格 数量
5 mg
¥ 720.00
10 mg
¥ 1,220.00
50 mg
¥ 3,600.00
100 mg
¥ 12,240.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

LY2109761是一种新型的I型和II型转化生长因子β受体双重抑制剂,对Smad2的磷酸化产生负面影响,作为抑制胰腺癌转移的治疗方法。
In vitro (25°C) DMSO 2 mg/mL (4.52 mM)
Water Insoluble
Ethanol Insoluble
In vivo 0.5% CMC+0.25% Tween 80 (suspensions) 15 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.65 mL 113.25 mL 226.5 mL
0.5 mM 4.53 mL 22.65 mL 45.3 mL
1 mM 2.27 mL 11.33 mL 22.65 mL
5 mM 0.45 mL 2.27 mL 4.53 mL

*The above data is based on the productmolecular weight 441.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11133
作用机制 Inhibitor (抑制剂)
M. Wt 441.5
Formula C26H27N5O2
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 700874-71-1
Synonyms LY-2109761
SMILES C1CC2=C(C(=NN2C1)C3=CC=CC=N3)C4=C5C=CC(=CC5=NC=C4)OCCN6CCOCC6

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