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Mavatrep是生物利用的TRPV1拮抗剂（Ki = 6.5 nM），对CYP亚型3A4、1A2和2D6的酶活性（IC50> 25μM）影响很小。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.67 mL | 118.36 mL | 236.72 mL |
| 0.5 mM | 4.73 mL | 23.67 mL | 47.34 mL |
| 1 mM | 2.37 mL | 11.84 mL | 23.67 mL |
| 5 mM | 0.47 mL | 2.37 mL | 4.73 mL |
*The above data is based on the productmolecular weight 422.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15778 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 422.44 |
| Formula | C25H21F3N2O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 956274-94-5 |
| Synonyms | JNJ-39439335 |
| SMILES | CC(C)(C1=CC=CC=C1C2=CC3=C(C=C2)N=C(N3)C=CC4=CC=C(C=C4)C(F)(F)F)O |
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