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MK-4827 (Niraparib)是一种新型有效的口服生物可利用的PARP-1和PARP-2抑制剂。
| In vitro (25°C) | DMSO | 60 mg/mL (187.27 mM) | |
| Water | Insoluble | ||
| Ethanol | 60 mg/mL (187.27 mM) | ||
| In vivo | 10% DMSO+40% PEG 300+5% Tween 80+ddH2O | 9 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.21 mL | 156.05 mL | 312.11 mL |
| 0.5 mM | 6.24 mL | 31.21 mL | 62.42 mL |
| 1 mM | 3.12 mL | 15.61 mL | 31.21 mL |
| 5 mM | 0.62 mL | 3.12 mL | 6.24 mL |
*The above data is based on the productmolecular weight 320.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A11026 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 320.4 |
| Formula | C19H20N4O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1038915-60-4 |
| Synonyms | MK4827 |
| SMILES | C1C[C@H](CNC1)C2=CC=C(C=C2)N3C=C4C=CC=C(C4=N3)C(=O)N |
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