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Nexturastat A

Nexturastat A

Name: Nexturastat A
SKU: A14032

目录号: A14032

HDAC6 抑制剂

Nexturastat A Chemical Structure

CAS NO. 1403783-31-2

Nexturastat A是一种芳基脲衍生物，可作为组蛋白脱乙酰基酶6（HDAC6）的有效且高度选择性的抑制剂（IC50 = 5.02+/-0.60 nM）。

库存：现货

规格	价格	数量
10 mg	￥ 1,200.00
25 mg	￥ 2,500.00
50 mg	￥ 3,500.00
10mM * 1mL in DMSO	￥ 800.00

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生物活性

Nexturastat A是一种芳基脲衍生物，可作为组蛋白脱乙酰基酶6（HDAC6）的有效且高度选择性的抑制剂（IC50 = 5.02+/-0.60 nM）。

靶点信息

HDAC6
5 nM

溶解度 *

In vitro	DMSO	59 mg/mL (172.81 mM)
	Water	Insoluble
	Ethanol	2 mg/mL (5.85 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	29.29 mL	146.45 mL	292.91 mL
0.5 mM	5.86 mL	29.29 mL	58.58 mL
1 mM	2.93 mL	14.65 mL	29.29 mL
5 mM	0.59 mL	2.93 mL	5.86 mL

*The above data is based on the productmolecular weight 341.40422. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A14032
作用机制	Inhibitor (抑制剂)
M. Wt	341.40422
Formula	C19H23N3O3
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1403783-31-2
Synonyms	Nexturastat-A,NexturastatA
SMILES	CCCCN(CC1=CC=C(C=C1)C(=O)NO)C(=O)NC2=CC=CC=C2