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NU-7441 (KU-57788)

NU-7441 (KU-57788)

Name: NU-7441 (KU-57788)
SKU: A11098

目录号: A11098

DNA-PK 抑制剂

Product Citations (4)

NU-7441 (KU-57788) Chemical Structure

CAS NO. 503468-95-9

NU-7441 (KU-57788)是一种有效的选择性DNA依赖性蛋白激酶（DNA-PK）抑制剂。对于DNA-PK，mTOR，PI 3-K，ATM和ATR，IC50值分别为14、1700、5000，> 100000和> 100000 nM。

库存：现货

规格	价格	数量
5 mg	￥ 500.00
10 mg	￥ 900.00
50 mg	￥ 1,800.00
100 mg	￥ 3,000.00

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生物活性

NU-7441 (KU-57788)是一种有效的选择性DNA依赖性蛋白激酶（DNA-PK）抑制剂。对于DNA-PK，mTOR，PI 3-K，ATM和ATR，IC50值分别为14、1700、5000，> 100000和> 100000 nM。

溶解度 *

In vitro (25°C)	DMSO	Warmed: 4 mg/mL (9.67 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5% DMSO+30% PEG 300+5% Tween 80+ddH2O	1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.18 mL	120.92 mL	241.84 mL
0.5 mM	4.84 mL	24.18 mL	48.37 mL
1 mM	2.42 mL	12.09 mL	24.18 mL
5 mM	0.48 mL	2.42 mL	4.84 mL

*The above data is based on the productmolecular weight 413.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11098
作用机制	Inhibitor (抑制剂)
M. Wt	413.5
Formula	C25H19NO3S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	503468-95-9
Synonyms	NU7441, KU57788
SMILES	C1COCCN1C2=CC(=O)C3=C(O2)C(=CC=C3)C4=CC=CC5=C4SC6=CC=CC=C56