NVP-BSK805

目录号: A11193

JAK 抑制剂

NVP-BSK805

NVP-BSK805 Chemical Structure

CAS NO. 1092499-93-8

NVP-BSK805是喹喔啉JAK2抑制剂对红细胞增多症的有效和选择性抑制,喹喔啉JAK2抑制剂可有效抑制小鼠和大鼠中重组人促红细胞生成素诱导的红细胞增多症和髓外红细胞生成。IC50为0.5 nM,比作用于JAK1, JAK3和TYK2选择性高20倍以上。

库存: 现货

规格 价格 数量
5 mg
¥ 1,400.00
10 mg
¥ 2,000.00
50 mg
¥ 5,800.00
100 mg
¥ 9,200.00
10mM * 1mL in DMSO
¥ 2,170.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

NVP-BSK805是喹喔啉JAK2抑制剂对红细胞增多症的有效和选择性抑制,喹喔啉JAK2抑制剂可有效抑制小鼠和大鼠中重组人促红细胞生成素诱导的红细胞增多症和髓外红细胞生成。IC50为0.5 nM,比作用于JAK1, JAK3和TYK2选择性高20倍以上。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.75 mL 88.74 mL 177.47 mL
0.5 mM 3.55 mL 17.75 mL 35.49 mL
1 mM 1.77 mL 8.87 mL 17.75 mL
5 mM 0.35 mL 1.77 mL 3.55 mL

*The above data is based on the productmolecular weight 563.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11193
作用机制 Inhibitor (抑制剂)
M. Wt 563.47
Formula C27H28F2N6O.2HCl
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1092499-93-8
Synonyms NVPBSK805
SMILES C1CNCCC1N2C=C(C=N2)C3=NC4=C(C=CC=C4N=C3)C5=CC(=C(C(=C5)F)CN6CCOCC6)F.Cl.Cl

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