OF-1

目录号: A16000

BRPF1B/BRPF2 bromodomain 抑制剂

OF-1

OF-1 Chemical Structure

CAS NO. 19973-83-4

OF-1是BRPF溴结构域的化学探针。OF-1已显示以100 nM的KD(ITC)结合到BRPF1B,以500 nM的KD(ITC)结合到BRPF2和以2.4 uM的KD(ITC)结合到BRPF3。

库存: 现货

规格 价格 数量
5 mg
¥ 800.00
10 mg
¥ 1,200.00
50 mg
¥ 5,200.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

OF-1是BRPF溴结构域的化学探针。OF-1已显示以100 nM的KD(ITC)结合到BRPF1B,以500 nM的KD(ITC)结合到BRPF2和以2.4 uM的KD(ITC)结合到BRPF3。
In vitro (25°C) DMSO Warmed: 72 mg/mL (163.52 mM)
Water Insoluble
Ethanol Insoluble
In vivo 5%DMSO+30%PEG300+5%Tween-80+ddH2O 2 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.71 mL 113.56 mL 227.11 mL
0.5 mM 4.54 mL 22.71 mL 45.42 mL
1 mM 2.27 mL 11.36 mL 22.71 mL
5 mM 0.45 mL 2.27 mL 4.54 mL

*The above data is based on the productmolecular weight 440.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A16000
作用机制 Inhibitor (抑制剂)
M. Wt 440.31
Formula C17H18BrN3O4S
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 19973-83-4
Synonyms OF1, OF 1
SMILES O=S(C1=CC=C(Br)C=C1C)(NC2=C(OC)C=C(N3C)C(N(C)C3=O)=C2)=O

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