产品详情
靶点信息
MEK1 (Cell-free assay) | ||||
2 μM |
In vitro (25°C) | DMSO | Warmed: 13 mg/mL (48.63 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 4% DMSO+30% PEG 300+5% Tween 80+ddH2O | 1 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 37.41 mL | 187.06 mL | 374.11 mL |
0.5 mM | 7.48 mL | 37.41 mL | 74.82 mL |
1 mM | 3.74 mL | 18.71 mL | 37.41 mL |
5 mM | 0.75 mL | 3.74 mL | 7.48 mL |
*The above data is based on the productmolecular weight 267.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A10705 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 267.3 |
Formula | C16H13NO3 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 167869-21-8 |
SMILES | COC1=CC=CC(=C1N)C2=CC(=O)C3=CC=CC=C3O2 |
产品标签
Product Questions
Product Questions
PD184352 (CI-1040)
PD184352 (CI-1040)是一种ATP非竞争性MEK1/2抑制剂,在基于细胞的测定中,IC50为17 nM,对MEK1/2的选择性是对MEK5的1…
TCS ERK 11e (VX-11e)
TCS ERK 11e (VX-11e)是一种有效且选择性的细胞外信号相关激酶2(ERK2)抑制剂(ERK2,GSK-3,Aurora激酶A和Cdk2的Ki…
Refametinib
Refametinib是一种有效的,ATP非竞争性和高度选择性的MEK1和MEK2抑制剂,IC50分别为19 nM和47 nM。