PF-04620110

Name: PF-04620110
SKU: A11526

目录号: A11526

DGAT1 抑制剂

PF-04620110 Chemical Structure

CAS NO. 1109276-89-2

PF-04620110是一种有效、选择性的，有口服活性的甘油二酯酰基转移酶-1 (DGAT1) 抑制剂，IC50值为 19 nM。

库存：现货

规格	价格	数量
10 mg	￥ 960.00
25 mg	￥ 2,200.00
50 mg	￥ 3,500.00
10mM * 1mL in DMSO	￥ 990.00

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生物活性

PF-04620110是一种有效、选择性的，有口服活性的甘油二酯酰基转移酶-1 (DGAT1) 抑制剂，IC50值为 19 nM。

靶点信息

DGAT1
19 nM

溶解度 *

In vitro	DMSO	Warmed: 46 mg/mL (116.03 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.22 mL	126.12 mL	252.24 mL
0.5 mM	5.04 mL	25.22 mL	50.45 mL
1 mM	2.52 mL	12.61 mL	25.22 mL
5 mM	0.5 mL	2.52 mL	5.04 mL

*The above data is based on the productmolecular weight 396.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11526
作用机制	Inhibitor (抑制剂)
M. Wt	396.44
Formula	C21H24N4O4
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1109276-89-2
Synonyms	PF04620110
SMILES	C1CC(CCC1CC(=O)O)C2=CC=C(C=C2)N3CCOC4=NC=NC(=C4C3=O)N