产品详情
靶点信息
Akt | PDK-1 | |||
2.7 μM(Ki) | 5.2 μM(Ki) |
In vitro (25°C) | DMSO | 75 mg/mL (183.1 mM) | |
Water | Insoluble | ||
Ethanol | 55 mg/mL (134.27 mM) | ||
In vivo | 5% DMSO+95% Corn oil | 4 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 24.41 mL | 122.07 mL | 244.14 mL |
0.5 mM | 4.88 mL | 24.41 mL | 48.83 mL |
1 mM | 2.44 mL | 12.21 mL | 24.41 mL |
5 mM | 0.49 mL | 2.44 mL | 4.88 mL |
*The above data is based on the productmolecular weight 409.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A11032 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 409.6 |
Formula | C20H31N3O2S2 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 1191951-57-1 |
Synonyms | PHT427 |
SMILES | CCCCCCCCCCCCC1=CC=C(C=C1)S(=O)(=O)NC2=NN=CS2 |
产品标签
Product Questions
Product Questions
AT7867 2HCl
AT7867 dihydrochloride是一种有效的ATP竞争性Akt1/2/3和p70S6K/PKA抑制剂,IC50分别为32 nM/17 nM/47 nM和85 nM/20 nM,在AGC…
GDC-0068 (Ipatasertib, RG-7440)
GDC-0068 (Ipatasertib,RG-7440)是一种选择性的,具有ATP竞争性的pan-Akt抑制剂,在无细胞试验中,其靶向Akt1、2和3…
Akt1 and Akt2-IN-1
Akt1 and Akt2-IN-1是Akt1(IC50 = 3.5 nM)和Akt2(IC50 = 42 nM)的变构抑制剂,具有有效且平衡的活性。