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PI3K-alpha inhibitor 1 是从专利US/20120088764A1中提取的PI3Kα抑制剂，化合物243，IC50 <0.1uM，PI3Kα抑制剂1还抑制HDAC（0.1uM≤IC50≤1uM）。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.7 mL | 98.51 mL | 197.02 mL |
| 0.5 mM | 3.94 mL | 19.7 mL | 39.4 mL |
| 1 mM | 1.97 mL | 9.85 mL | 19.7 mL |
| 5 mM | 0.39 mL | 1.97 mL | 3.94 mL |
*The above data is based on the productmolecular weight 507.57. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16274 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 507.57 |
| Formula | C23H25N9O3S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1235449-52-1 |
| SMILES | CN(CC1=CC(N=C(C2=CN=C(NC)C=C2)N=C3N4CCOCC4)=C3S1)C5=NC=C(C(NO)=O)C=N5 |
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