PIK-75 hydrochloride

目录号: A10729

PI3K 抑制剂

PIK-75 hydrochloride

PIK-75 hydrochloride Chemical Structure

CAS NO. 372196-77-5

PIK-75是一种p110α抑制剂,IC50值为5.8nM。在p110γ和p110β的效果较差,IC50值为0.076 ?M和1.3 ?M。

库存: 现货

规格 价格 数量
10 mg
¥ 400.00
25 mg
¥ 700.00
50 mg
¥ 1,200.00
100 mg
¥ 1,700.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

PIK-75是一种p110α抑制剂,IC50值为5.8nM。在p110γ和p110β的效果较差,IC50值为0.076 ?M和1.3 ?M。
靶点信息
DNA-PK (Cell-free assay) p110α (Cell-free assay) p110γ (Cell-free assay) p110δ (Cell-free assay) p110β (Cell-free assay)
2 nM5.8 nM76 nM0.51 μM1.3 μM
In vitro DMSO Warmed: 4 mg/mL (8.18 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.46 mL 102.31 mL 204.62 mL
0.5 mM 4.09 mL 20.46 mL 40.92 mL
1 mM 2.05 mL 10.23 mL 20.46 mL
5 mM 0.41 mL 2.05 mL 4.09 mL

*The above data is based on the productmolecular weight 488.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10729
作用机制 Inhibitor (抑制剂)
M. Wt 488.7
Formula C16H14BrN5O4S.HCl
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 372196-77-5
Synonyms PIK75
SMILES CC1=C(C=C(C=C1)[N+](=O)[O-])S(=O)(=O)N(C)/N=C/C2=CN=C3N2C=C(C=C3)Br.Cl

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