Plerixafor 8HCl (DB06809)

目录号: A10913

CXCR4 拮抗剂

Plerixafor 8HCl (DB06809)

Plerixafor 8HCl (DB06809) Chemical Structure

CAS NO. 155148-31-5

Plerixafor 8HCl (DB06809)是CXCR4趋化因子受体拮抗剂,作用于CXCR4和CXCL12介导调节的趋化性, IC50分别为44 nM和5.7 nM。

库存: 现货

规格 价格 数量
10 mg
¥ 600.00
25 mg
¥ 1,000.00
50 mg
¥ 1,600.00
100 mg
¥ 3,100.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Plerixafor 8HCl (DB06809)是CXCR4趋化因子受体拮抗剂,作用于CXCR4和CXCL12介导调节的趋化性, IC50分别为44 nM和5.7 nM。
靶点信息
CXCL12-mediated chemotaxis (Cell-free assay) CXCR4 (Cell-free assay)
5.7 nM44 nM
In vitro (25°C) DMSO Insoluble
Water 91 mg/mL (114.54 mM)
Ethanol Insoluble
In vivo Saline 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 12.59 mL 62.93 mL 125.87 mL
0.5 mM 2.52 mL 12.59 mL 25.17 mL
1 mM 1.26 mL 6.29 mL 12.59 mL
5 mM 0.25 mL 1.26 mL 2.52 mL

*The above data is based on the productmolecular weight 794.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10913
作用机制 Antagonist (拮抗剂)
M. Wt 794.5
Formula C28H54N8.8HCl
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 155148-31-5
Synonyms DB06809, AMD3100, Mozobil
SMILES C1CNCCNCCCN(CCNC1)CC2=CC=C(C=C2)CN3CCCNCCNCCCNCC3.Cl.Cl.Cl.Cl.Cl.Cl.Cl.Cl

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