2018-2019 AdooQ 最新目录册 点击此处下载

PPAR

30 个项目

每页

设置升序顺序
Catalog No. Product Name Application Product Information
A14958 SALE

GW0742

PPAR 激动剂
GW0742 is a selective agonist of PPARδ with EC50 value of 1.1 nM.
A16309

DG172 dihydrochloride

PPAR??/?? inverse 激动剂
DG-172 is an orally active potent PPARβ/δ inverse agonist (IC50 = 26.9 nM). DG-172 inhibits Angptl4 gene expression in mouse myoblasts (IC50 = 9.5 nM) in vitro.
A16308

CDDO-Im

PPAR?? 激动剂
CDDO-Im is a novel synthetic triterpenoid more potent than its parent compound CDDO both in vitro and in vivo; PPARγ Agonist.
A15454 SALE

Elafibranor

PPAR 激动剂
Elafibranor is an agonist of the peroxisome proliferator-activated Receptor-α and -δ, induces resolution of nonalcoholic steatohepatitis without fibrosis worsening.
A12492

Aleglitazar

PPAR-??/?? 激动剂
Aleglitazar is a new dual PPAR-α/γ agonist with IC50 of 2.8 nM/4.6 nM.
A11588 SALE

T0070907

PPAR-?? 拮抗剂
T0070907 was identified as a potent and selective PPARgamma antagonist. With an apparent binding affinity (concentration at 50% inhibition of [(3)H]rosiglitazone binding or IC(50)) of 1 nm, T0070907 covalently modifies PPARgamma on cysteine 313 in helix 3 of human PPARgamma2.
A15836 SALE

BMS-687453

PPAR 激动剂
BMS-687453 is a potent and selective peroxisome proliferator activated receptor (PPAR) alpha agonist, with an EC(50) of 10 nM for human PPARalpha and approximately 410-fold selectivity vs human PPARgamma in PPAR-GAL4 transactivation assays.
A15013 SALE

Balaglitazone

PPAR-?? partial 激动剂
Balaglitazone is a novel partial agonist of PPAR-gamma (γ).
A15099

GW1929

PPAR 激动剂
GW1929 is a synthetic peroxisome proliferator-activated receptor-?? (PPAR??) agonist with IC50 of 6.2 nM and 13 nM for human and mouse, respectively.
A11437

GW 501516

PPAR?? receptor 激动剂
GW501516 (GW1516 or GSK-516) is a drug that acts as a PPAR?? modulator.
A12391 SALE

GSK-3787

PPAR 拮抗剂
GSK-3787 is a potent and selective peroxisome proliferator-activated receptor δ (PPARδ) antagonist (pIC50 = 6.6).
A12392 SALE

GSK 0660

PPAR?? 拮抗剂
GSK 0660 is a selective PPARβ antagonist (IC50 values are 0.155, > 10 and ≥ 10 µM at PPARβ, PPARα and PPARγ respectively).
A12413

GW6471

PPAR?? 拮抗剂
GW6471 is a PPARα antagonist, shown to completely inhibit GW409544-induced activation of PPARα.
A15044

Choline Fenofibrate

CYP2C19/CYP2B6 抑制剂
Choline Fenofibrate (ABT-335) is the choline salt of fenofibric acid under clinical development as a combination therapy with rosuvastatin for the management of dyslipidemia.
A15129

Inolitazone dihydrochloride

PPAR?? 激动剂
Inolitazone dihydrochloride is a novel high-affinity PPARγ agonist, which activates PPARγ with an EC50 about 1/50 that of rosiglitazone and has no effect on RIE cells.
A16001

Fenofibric acid

-
Fenofibric acid is a fibrate that acts as a lipid-lowering agent, decreasing low-density lipoprotein cholesterol and triglycerides.
A10385

Fenofibrate

-
Fenofibrate is a drug of the fibrate class. It is mainly used to reduce cholesterol levels in patients at risk of cardiovascular disease.
A16307

Bezafibrate

PPAR 激动剂
Bezafibrate is the first clinically tested dual and pan-PPAR co-agonist.
A12360 SALE

pirinixic acid (WY 14643)

PPAR?? 激动剂
WY 14643 is a highly potent PPARα agonist.
A10424 SALE

Gemfibrozil (Lopid)

-
Gemfibrozil (Lopid) is a compound used to lower lipid levels.
A10809 SALE

Rosiglitazone maleate

PPAR 激动剂
Rosiglitazone maleate, an antidiabetic drug, works as an insulin sensitizer, by binding to the PPAR receptors in fat cells and making the cells more responsive to insulin.
A11137 SALE

Cetaben

Peroxisome Proliferator
Cetaben is a unique, PPARα-independent peroxisome proliferator with hypolipidemic activity that inhibits cholesterol synthesis in the human hepatoma Hep-G2 cells resulting in reversible changes in Golgi morphology.
A11680 SALE

Pioglitazone (Actos)

PPAR?? 激动剂
Pioglitazone selectively stimulates the nuclear receptor peroxisome proliferator-activated receptor gamma (PPAR-γ) and to a lesser extent PPAR-α.
A10807 SALE

Rosiglitazone (BRL-49653)

PPAR 激动剂
Rosiglitazone works as an insulin sensitizer, by binding to the PPAR receptors in fat cells and making the cells more responsive to insulin.
A11727 SALE

Ciprofibrate

-
Ciprofibrate is a fibrate.
A11981 SALE

Troglitazone

PPAR?? 激动剂
Troglitazone is a selective PPARγ receptor agonist (EC50 values are 780 and 555 nM at murine and human PPARγ receptors respectively).
A11982

GW 7647

PPAR?? 激动剂
GW 7647 is a potent and highly selective PPARα agonist (EC50 values are 6, 1100 and 6200 nM for human PPARα, PPARγ and PPARδ receptors respectively).
A11983 SALE

L-165,041

PPAR?? 激动剂
L-165,041 is a potent PPARδ agonist (Ki = 6 nM); displays > 100-fold selectivity for both mouse and human PPARδ receptors over other subtypes.
A11984 SALE

GW 9662

PPAR?? 拮抗剂
GW 9662 is a selective PPARγ antagonist (IC50 values are 3.3, 32 and 2000 nM for PPARγ, PPARα and PPARδ respectively).
A16463

Clofibric Acid

PPAR?? 激动剂
Clofibric acid is a PPARα agonist and hypolipidemic agent.

30 个项目

每页

设置升序顺序