PRX-08066

目录号: A13267

5-HT2B receptor 拮抗剂

PRX-08066

PRX-08066 Chemical Structure

CAS NO. 866206-54-4

PRX-08066是一种新型的5-HT受体2B(5-HT2BR)拮抗剂,IC50为3.4 nM,,可减轻单芥子碱诱导的大鼠肺动脉高压和右室肥大。

库存: 现货

规格 价格 数量
5 mg
¥ 1,900.00
10 mg
¥ 2,800.00
25 mg
¥ 5,700.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

PRX-08066是一种新型的5-HT受体2B(5-HT2BR)拮抗剂,IC50为3.4 nM,,可减轻单芥子碱诱导的大鼠肺动脉高压和右室肥大。
In vitro DMSO 92 mg/mL (177.61 mM)
Water 92 mg/mL (177.61 mM)
Ethanol 86 mg/mL (166.03 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.88 mL 124.41 mL 248.82 mL
0.5 mM 4.98 mL 24.88 mL 49.76 mL
1 mM 2.49 mL 12.44 mL 24.88 mL
5 mM 0.5 mL 2.49 mL 4.98 mL

*The above data is based on the productmolecular weight 401.89. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A13267
作用机制 Antagonist (拮抗剂)
M. Wt 401.89
Formula C19H17ClFN5S
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 866206-54-4
Synonyms PRX08066, PRX 08066
SMILES C1CN(CCC1NC2=C3C=C(SC3=NC=N2)Cl)CC4=CC(=C(C=C4)F)C#N

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