PTC-209 HBr

Name: PTC-209 HBr
SKU: A14280

目录号: A14280

BMI-1 抑制剂

PTC-209 HBr Chemical Structure

CAS NO. 1217022-63-3

PTC-209 HBr是PTC-209的氢溴酸盐。PTC-209是一种有效的选择性BMI-1抑制剂，在HEK293T细胞系中的IC50为0.5μM，可导致癌症起始细胞（CIC）不可逆地减少。

库存：现货

规格	价格	数量
10 mg	￥ 1,200.00
25 mg	￥ 2,200.00
50 mg	￥ 3,800.00
10mM * 1mL in DMSO	￥ 1,280.00

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生物活性

PTC-209 HBr是PTC-209的氢溴酸盐。PTC-209是一种有效的选择性BMI-1抑制剂，在HEK293T细胞系中的IC50为0.5μM，可导致癌症起始细胞（CIC）不可逆地减少。

靶点信息

BMI-1
0.5 μM

溶解度 *

In vitro (25°C)	DMSO	Warmed: 99 mg/mL (171.84 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	2% DMSO+35% PEG 300+2% Tween 80+ddH2O	6 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.36 mL	86.79 mL	173.58 mL
0.5 mM	3.47 mL	17.36 mL	34.72 mL
1 mM	1.74 mL	8.68 mL	17.36 mL
5 mM	0.35 mL	1.74 mL	3.47 mL

*The above data is based on the productmolecular weight 576.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A14280
作用机制	Inhibitor (抑制剂)
M. Wt	576.1
Formula	C17H13Br2N5OS.HBr
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1217022-63-3
Synonyms	PTX209
SMILES	CC1=C(N2C=CC=NC2=N1)C3=CSC(=N3)NC4=C(C=C(C=C4Br)OC)Br.Br