Purvalanol B

目录号: A12352

CDK 抑制剂

Purvalanol B

Purvalanol B Chemical Structure

CAS NO. 212844-54-7

Purvalanol B是一种细胞周期蛋白依赖性激酶抑制剂。对于cdc2/cyclin B,cdk2/cyclin A,cdk2/cyclin E,cdk4/cyclin D1和cdk5-p35的ic50值分别为6、6、9、> 10,000和6 nm。对一系列其他蛋白激酶具有选择性(IC50 > 10,000 nM)。

库存: 现货

规格 价格 数量
10 mg
¥ 890.00
25 mg
¥ 1,780.00
50 mg
¥ 2,670.00
100 mg
¥ 4,450.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Purvalanol B是一种细胞周期蛋白依赖性激酶抑制剂。对于cdc2/cyclin B,cdk2/cyclin A,cdk2/cyclin E,cdk4/cyclin D1和cdk5-p35的ic50值分别为6、6、9、> 10,000和6 nm。对一系列其他蛋白激酶具有选择性(IC50 > 10,000 nM)。
In vitro DMSO 84 mg/mL (194.04 mM)
Water <1 mg/mL
Ethanol <1 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.1 mL 115.5 mL 230.99 mL
0.5 mM 4.62 mL 23.1 mL 46.2 mL
1 mM 2.31 mL 11.55 mL 23.1 mL
5 mM 0.46 mL 2.31 mL 4.62 mL

*The above data is based on the productmolecular weight 432.91. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12352
作用机制 Inhibitor (抑制剂)
M. Wt 432.91
Formula C20H25ClN6O3
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 212844-54-7
Synonyms NG 95
SMILES CC(C)[C@H](CO)NC1=NC2=C(C(=N1)NC3=CC(=C(C=C3)C(=O)O)Cl)N=CN2C(C)C

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