PX-478 HCl

Name: PX-478 HCl
SKU: A14319

目录号: A14319

HIF-1alpha 抑制剂

PX-478 HCl Chemical Structure

CAS NO. 685898-44-6

PX-478 HCl是HIF-1alpha抑制剂，也是具有潜在抗肿瘤活性小分子。PX-478对已建立的人类肿瘤异种移植物具有出色的活性，可提供具有HIF-1水平正相关的延长的生长延迟的肿瘤消退。PX-478是高度水溶性的分子，具有良好的i.v.，i.p.和p.o.抗肿瘤活性。

库存：现货

规格	价格	数量
10 mg	￥ 1,400.00
25 mg	￥ 2,500.00
50 mg	￥ 3,500.00
10mM * 1mL in DMSO	￥ 850.00

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产品仅用于科学研究，不针对患者销售，望谅解.

产品详情

生物活性

靶点信息

HIF-1α

溶解度 *

In vitro	DMSO	73 mg/mL (185.21 mM)
	Water	73 mg/mL (185.21 mM)
	Ethanol	73 mg/mL (185.21 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.37 mL	126.86 mL	253.73 mL
0.5 mM	5.07 mL	25.37 mL	50.75 mL
1 mM	2.54 mL	12.69 mL	25.37 mL
5 mM	0.51 mL	2.54 mL	5.07 mL

*The above data is based on the productmolecular weight 394.12. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A14319
作用机制	Inhibitor (抑制剂)
M. Wt	394.12
Formula	C13H20Cl4N2O3
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	685898-44-6
Synonyms	0
SMILES	C1=CC(=CC=C1C[C@@H](C(=O)O)N)[N+](CCCl)(CCCl)[O-].Cl.Cl