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(-)-JQ1蛋白家族蛋白质的溴结构域和额外末端结构域（BET）家族，包括BRD2，BRD3和BRD4，在许多细胞过程中起着关键作用，包括炎症基因表达，有丝分裂和病毒/宿主相互作用，这是通过控制组蛋白乙酰化的过程来实现的。依赖的染色质复合物。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.88 mL | 109.41 mL | 218.82 mL |
| 0.5 mM | 4.38 mL | 21.88 mL | 43.76 mL |
| 1 mM | 2.19 mL | 10.94 mL | 21.88 mL |
| 5 mM | 0.44 mL | 2.19 mL | 4.38 mL |
*The above data is based on the productmolecular weight 457. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A14160 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 457 |
| Formula | C23H25ClN4O2S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1268524-71-5 |
| SMILES | CC1=C(SC2=C1C(=N[C@@H](C3=NN=C(N32)C)CC(=O)OC(C)(C)C)C4=CC=C(C=C4)Cl)C |
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