R428

目录号: A13741

Axl 抑制剂

R428

R428 Chemical Structure

CAS NO. 1037624-75-1

R428是Axl激酶的选择性小分子抑制剂,在转移性乳腺癌模型中显示出阻断肿瘤扩散和延长生存期的活性。

库存: 现货

规格 价格 数量
2 mg
¥ 500.00
5 mg
¥ 900.00
10 mg
¥ 1,600.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

R428是Axl激酶的选择性小分子抑制剂,在转移性乳腺癌模型中显示出阻断肿瘤扩散和延长生存期的活性。
靶点信息
Axl
14 nM
In vitro (25°C) DMSO Warmed: 6 mg/mL (11.84 mM)
Water Insoluble
Ethanol Insoluble
In vivo 5% DMSO+corn oil 1 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.74 mL 98.69 mL 197.38 mL
0.5 mM 3.95 mL 19.74 mL 39.48 mL
1 mM 1.97 mL 9.87 mL 19.74 mL
5 mM 0.39 mL 1.97 mL 3.95 mL

*The above data is based on the productmolecular weight 506.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A13741
作用机制 Inhibitor (抑制剂)
M. Wt 506.64
Formula C30H34N8
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1037624-75-1
Synonyms BGB324, BGB 324, BGB-324, R-428
SMILES C1CCN(C1)[C@H]2CCC3=C(CC2)C=C(C=C3)NC4=NN(C(=N4)N)C5=NN=C6C(=C5)CCCC7=CC=CC=C76

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