R788 (Fostamatinib)

目录号: A11926

Syk 抑制剂

R788 (Fostamatinib)

R788 (Fostamatinib) Chemical Structure

CAS NO. 901119-35-5

R788 (Fostamatinib)是重要的脾酪氨酸激酶(Syk)抑制剂,显示出对激酶介导的IgG Fcγ受体信号转导的功效。

库存: 现货

规格 价格 数量
2 mg
¥ 500.00
5 mg
¥ 800.00
10 mg
¥ 1,400.00
25 mg
¥ 2,800.00
10mM * 1mL in DMSO
¥ 1,200.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

R788 (Fostamatinib)是重要的脾酪氨酸激酶(Syk)抑制剂,显示出对激酶介导的IgG Fcγ受体信号转导的功效。
靶点信息
Syk Adenosine A3 receptor Adenosine transporter Monoamine transporter
41 nM81 nM1.84 μM2.74 μM
In vitro (25°C) DMSO 107 mg/mL (184.34 mM)
Water Insoluble
Ethanol Insoluble
In vivo 4% DMSO+30% PEG 300+ddH2O 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.23 mL 86.13 mL 172.27 mL
0.5 mM 3.45 mL 17.23 mL 34.45 mL
1 mM 1.72 mL 8.61 mL 17.23 mL
5 mM 0.34 mL 1.72 mL 3.45 mL

*The above data is based on the productmolecular weight 580.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11926
作用机制 Inhibitor (抑制剂)
M. Wt 580.5
Formula C23H26FN6O9P
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 901119-35-5
Synonyms R-788
SMILES CC1(C(=O)N(C2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)COP(=O)(O)O)C

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