Raltegravir (MK-0518)

目录号: A10775

HIV-1 integrase 抑制剂

Raltegravir (MK-0518)

Raltegravir (MK-0518) Chemical Structure

CAS NO. 518048-05-0

Raltegravir (MK-0518)靶向整合酶,这是一种HIV酶,可将病毒遗传物质整合到人类染色体中,这是HIV发病机理中的关键步骤。

库存: 现货

规格 价格 数量
5 mg
¥ 450.00
10 mg
¥ 650.00
50 mg
¥ 1,600.00
100 mg
¥ 2,550.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Raltegravir (MK-0518)靶向整合酶,这是一种HIV酶,可将病毒遗传物质整合到人类染色体中,这是HIV发病机理中的关键步骤。
In vitro (25°C) DMSO 80 mg/mL (180.01 mM)
Water Insoluble
Ethanol Insoluble
In vivo 2% DMSO+40% PEG 300+2% Tween 80+ddH2O 7 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.5 mL 112.51 mL 225.02 mL
0.5 mM 4.5 mL 22.5 mL 45 mL
1 mM 2.25 mL 11.25 mL 22.5 mL
5 mM 0.45 mL 2.25 mL 4.5 mL

*The above data is based on the productmolecular weight 444.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10775
作用机制 Inhibitor (抑制剂)
M. Wt 444.4
Formula C20H21FN6O5
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 518048-05-0
Synonyms Isentress, MK0518, MK-0518
SMILES CC1=NN=C(O1)C(=O)NC(C)(C)C2=NC(=C(C(=O)N2C)[O-])C(=O)NCC3=CC=C(C=C3)F.[K+]

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