Rapamycin (Sirolimus)

目录号: A10782

mTOR 抑制剂

Rapamycin (Sirolimus)

Rapamycin (Sirolimus) Chemical Structure

CAS NO. 53123-88-9

Rapamycin (Sirolimus)是通过抑制T细胞和B细胞对白介素2(IL-2)的反应来防止其活化。

库存: 现货

规格 价格 数量
5 mg
¥ 400.00
50 mg
¥ 550.00
100 mg
¥ 700.00
10mM * 1mL in DMSO
¥ 500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Rapamycin (Sirolimus)是通过抑制T细胞和B细胞对白介素2(IL-2)的反应来防止其活化。
靶点信息
mTOR (HEK293 cells)
~0.1 nM
In vitro (25°C) DMSO 18 mg/mL (19.68 mM)
Water Insoluble
Ethanol Insoluble
In vivo 2% DMSO+30% PEG 300+5% Tween 80+ddH2O 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 10.94 mL 54.69 mL 109.39 mL
0.5 mM 2.19 mL 10.94 mL 21.88 mL
1 mM 1.09 mL 5.47 mL 10.94 mL
5 mM 0.22 mL 1.09 mL 2.19 mL

*The above data is based on the productmolecular weight 914.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10782
作用机制 Inhibitor (抑制剂)
M. Wt 914.2
Formula C51H79NO13
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 53123-88-9
Synonyms Rapamune
SMILES C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)O)C)/C)O)OC)C)C)/C)OC

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