“rasgap ras p21”的搜索结果

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    Ras-IN-3144

    Catalog No. A17222
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    pan-RAS inhibitor
    Ras-IN-3144 is a pan-RAS inhibitor which inhibits RAS signaling pathways in cancer cells and prevents the growth of RAS mutant mouse cancer xenografts. 了解更多
  1. K-Ras-IN-1

    Catalog No. A20875
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    K-Ras inhibitor
    K-Ras-IN-1 is a K-Ras inhibitor, by binding to K-Ras in a hydrophobic pocket that is occupied by Tyr-71 in the apo-Ras crystal structure.(the detailed information refer to the reference). 了解更多
  2. K-Ras G12C-IN-1

    Catalog No. A20937
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    K-ras G12C inhibitor
    K-Ras G12C-IN-1 is a novel and irreversible inhibitor of mutant K-ras G12C extracted from patent WO 2014152588 A1. 了解更多
  3. K-Ras G12C-IN-2

    Catalog No. A20936
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    covalent K-Ras G12C inhibitor
    K-Ras G12C-IN-2 is an irreversible covalent K-Ras G12C inhibitor. 了解更多
  4. K-Ras G12C-IN-3

    Catalog No. A20931
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    K-ras G12C inhibitor
    K-Ras G12C-IN-3 is a novel and irreversible inhibitor of mutant K-ras G12C. 了解更多
  5. K-Ras(G12C) inhibitor 9

    Catalog No. A14250
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    K-Ras(G12C) 抑制剂
    K-Ras(G12C) inhibitor 9是致癌性K-Ras(G12C)的变构抑制剂。 了解更多
  6. Pluripotin (SC-1)

    Catalog No. A11225
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    ERK1/RasGAP 抑制剂
    Pluripotin (SC-1)的活性是通过联合抑制RasGAP和ERK1介导的,其Kd值分别为98和212 nM。 了解更多
  7. K-Ras(G12C) inhibitor 12

    Catalog No. A14227
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    K-Ras(G12C) 抑制剂
    K-Ras(G12C) inhibitor 12 是致癌性K-Ras(G12C)的变构抑制剂。 了解更多
  8. K-Ras(G12C) inhibitor 6

    Catalog No. A14103
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    K-Ras(G12C) 抑制剂
    K-Ras(G12C) inhibitor 6 是致癌性K-Ras(G12C)的不可逆抑制剂,颠覆了天然核苷酸的偏爱性,使GDP优于GTP。 了解更多
  9. G-5555

    Catalog No. A20702
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    PAK1 inhibitor
    G-5555 is a potent p21-activated kinase 1 (PAK1) inhibitor with Kis of 3.7 nM and 11 nM for PAK1 and PAK2, respectively. 了解更多
  10. WS-383

    Catalog No. A21483
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    DCN1-UBC12 interaction inhibitor
    WS-383 is a potent, selective and reversible inhibitor of DCN1-UBC12 interaction, with an IC50 of 11 nM. WS-383 inhibits Cul3/1 neddylation, induces accumulation of p21, p27 and NRF2. 了解更多
  11. 5-Aminosalicylic Acid

    Catalog No. A10570
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    PPARγ agonist
    5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB. 了解更多
  12. PAK4 Human

    Catalog No. AP4634
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    p21 Activated Kinase 4 Human Recombinant 了解更多
  13. Pifithrin-alpha

    Catalog No. A12451
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    p53 抑制剂
    Pifithrin-alpha是p53介导的细胞凋亡和p53依赖性基因转录(如细胞周期蛋白G,p21/waf1和mdm2表达)的可逆抑制剂。 了解更多
  14. MCP110

    Catalog No. A22317
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    inhibitor of Ras/Raf-1 interaction
    MCP110 is an inhibitor of Ras/Raf-1 interaction. MCP110 blocks the interaction of Ras with Raf. MCP110 disrupts this interaction might can be used for the research of human tumors. 了解更多
  15. 6H05

    Catalog No. A16097
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    K-Ras 抑制剂
    6H05是致癌突变体K-Ras(G12C)的选择性变构抑制剂。 了解更多
  16. (Rac)-Antineoplaston A10

    Catalog No. A21689
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    Ras inhibitor
    (rac)-Antineoplaston A10 is the racemate of Antineoplaston A10. Antineoplaston A10 is a Ras inhibitor potentially for the treatment of glioma, lymphoma, astrocytoma and breast cancer. 了解更多
  17. 6H05 (TFA)

    Catalog No. A21377
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    K-Ras(G12C) inhibitor
    6H05 TFA is a selective, and allosteric inhibitor of oncogenic mutant K-Ras(G12C). 了解更多
  18. ARS-1323

    Catalog No. A17060
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    mutant K-ras G12C 抑制剂
    ARS-1323是突变K-ras G12C的新型抑制剂。 了解更多
  19. ARS-1630

    Catalog No. A17061
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    mutant K-ras G12C 抑制剂
    ARS-1630是突变K-ras G12C的新型抑制剂。 了解更多
  20. RRAS Human

    Catalog No. AP2219
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    Related RAS Viral (r-ras) Oncogene Homolog Human Recombinant 了解更多
  21. RRAS2 Human

    Catalog No. AP2142
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    Related RAS Viral (r-ras) Oncogene Homolog 2 Human Recombinant 了解更多
  22. APS-2-79 HCl

    Catalog No. A16175
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    KSR/Ras 抑制剂
    APS-2-79 HCl,稳定KSR(Ras激酶抑制剂)失活状态并拮抗致癌性Ras信号(IC50值为120 nM,对抗KSR2的ATP-生物素探针标记)的小分子。 了解更多
  23. Resminostat hydrochloride

    Catalog No. A15220
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    HDAC 抑制剂
    Resminostat hydrochloride是HDAC1/3/6的有效抑制剂(IC50 = 43-72 nM);对HDAC8的效力较低,IC50为877 nM。 了解更多
  24. 6H05 (trifluoroacetate salt)

    Catalog No. A14235
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    K-Ras 抑制剂
    6H05 (trifluoroacetate salt)是致癌性K-Ras(G12C)的选择性变构抑制剂。 了解更多
  25. Kobe2602

    Catalog No. A12578
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    Ras–Raf 抑制剂
    Kobe2602是Kobe0065的类似物。表现出有效的活性以竞争性抑制Ki-值为149±55 μM的H-Ras·GTP与c-Raf-1 RBD的结合。 了解更多
  26. FTI 277

    Catalog No. A12368
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    FTase 抑制剂
    FTI 277是一种抑制法呢基转移酶(FTase)的抑制剂(IC50 = 0.5 nM)。抑制全细胞的 H-Ras 和 K-Ras 加工(IC50值分别为0.1和10 nM),破坏mapk的组成型H-Ras特异性激活。在人恶性胶质瘤细胞和许多其他肿瘤细胞系中引起显著的抗增殖作用。 了解更多
  27. Lonafarnib (SCH66336)

    Catalog No. A12328
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    FPTase 抑制剂
    Lonafarnib (SCH66336)是H-ras、K-ras-4B和N-ras的选择性FPTase抑制剂,IC50分别为1.9 nM、5.2 nM和2.8 nM。 了解更多
  28. ML162

    Catalog No. A22418
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    GPX4 inhibitor
    ML162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor. ML162 has a selective lethal effect on mutant RAS oncogene-expressing cell lines. 了解更多
  29. GGTI298

    Catalog No. A20418
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    GGTase I inhibitor
    GGTI298 is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor, strongly inhibiting the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras, with IC50 values of 3 and > 20 μM in vivo, respectively. 了解更多
  30. KY1220

    Catalog No. A20284
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    KY1220 is a compound that destabilizes both β-catenin and Ras, via targeting the Wnt/β-catenin pathway; with an IC50 of 2.1 μM in HEK293 reporter cells. 了解更多
  31. CID-1067700

    Catalog No. A21560
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    pan GTPase inhibitor
    CID-1067700 (ML282) is a pan GTPase inhibitor, and competitively inhibits Ras-related in brain 7 (Rab7) with a Ki of 13 nM. 了解更多
  32. GGTI298 Trifluoroacetate

    Catalog No. A16560
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    GGTase I inhibitor
    GGTI298 Trifluoroacetate is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor, which can inhibit Rap1A with IC50 of 3 μM; little effect on Ha-Ras with IC50 of >20 μM. 了解更多
  33. (S)-(-)-Perillyl alcohol

    Catalog No. A18817
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    (S)-(?)-Perillyl alcohol is a monoterpene found in lavender, inhibits farnesylation of Ras, upregulates the mannose-6-phosphate receptor and induces apoptosis. Anti-cancer activity. 了解更多
  34. RTC-5

    Catalog No. A19067
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    RTC-5 is an optimized phenothiazine with anti-cancer potency. RTC-5 demonstrates efficacy against a xenograft model of an EGFR driven cancer, its effects is attributed to concomitant negative regulation of PI3K-AKT and RAS-ERK signaling. 了解更多
  35. PHT-7.3

    Catalog No. A18473
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    Cnk1 inhibitor
    PHT-7.3 is a selective inhibitor of connector enhancer of kinase suppressor of Ras 1 (Cnk1) pleckstrin homology (PH) domain, which inhibits mut-KRas, but not wild-type KRas cancer cell and tumor growth and signaling. 了解更多
  36. FGTI-2734

    Catalog No. A18578
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    FT/GGT dual inhibitor
    FGTI-2734 is a RAS C-terminal mimetic dual farnesyl transferase (FT) and geranylgeranyl transferase-1 (GGT) inhibitor with IC50s of 250 nM and 520 nM for FT and GGT, respectively. 了解更多
  37. Antineoplaston A10

    Catalog No. A17183
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    Ras 抑制剂
    Antineoplaston A 10是Ras抑制剂,可能用于治疗神经胶质瘤,淋巴瘤,星形细胞瘤和乳腺癌。 了解更多
  38. RAB7A Antibody

    Catalog No. AP3223
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    Mouse Anti Human RAB7A, Member RAS Oncogene Family 了解更多
  39. RAB27A Antibody

    Catalog No. AP3187
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    RAB27A, Member RAS Oncogene Family, Mouse Anti Human 了解更多
  40. RAP2B Antibody

    Catalog No. AP3139
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    RAP2B, Member RAS Oncogene Family, Mouse Anti Human 了解更多
  41. RASSF1A Antibody

    Catalog No. AP3087
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    Ras association domain-containing protein 1, Mouse Anti Human 了解更多
  42. RAC2 Antibody

    Catalog No. AP2985
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    Ras-Related C3 Botulinum Toxin Substrate 2, Mouse Anti Human 了解更多
  43. NRAS Antibody

    Catalog No. AP2980
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    Neuroblastoma RAS Viral Oncogene Homolog, Mouse Anti Human 了解更多
  44. RAB34 Human

    Catalog No. AP2383
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    RAB34, Member RAS Oncogene Family Human Recombinant 了解更多
  45. RAB23 Human

    Catalog No. AP2382
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    RAB23, Member RAS Oncogene Family Human Recombinant 了解更多
  46. RAB18 Human

    Catalog No. AP2381
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    RAB18, Member RAS Oncogene Family Human Recombinant 了解更多
  47. RAB24 Human

    Catalog No. AP2357
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    RAB24, Member RAS Oncogene Family Human Recombinant 了解更多
  48. RAB32 Human

    Catalog No. AP2356
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    RAB32, Member RAS Oncogene Family Human Recombinant 了解更多
  49. RAB35 Human

    Catalog No. AP2341
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    RAB35, Member RAS Oncogene Family Human Recombinant 了解更多

产品 1 到 50 共 1051个

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