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Resminostat hydrochloride是HDAC1/3/6的有效抑制剂（IC50 = 43-72 nM）；对HDAC8的效力较低，IC50为877 nM。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.92 mL | 129.58 mL | 259.15 mL |
| 0.5 mM | 5.18 mL | 25.92 mL | 51.83 mL |
| 1 mM | 2.59 mL | 12.96 mL | 25.92 mL |
| 5 mM | 0.52 mL | 2.59 mL | 5.18 mL |
*The above data is based on the productmolecular weight 385.87. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15220 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 385.87 |
| Formula | C16H20ClN3O4S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1187075-34-8 |
| Synonyms | RAS2410 hydrochloride, 4SC-201 hydrochloride, RAS 2410 hydrochloride, RAS-2410 hydrochloride |
| SMILES | CN(C)CC1=CC=C(C=C1)S(=O)(=O)N2C=CC(=C2)C=CC(=O)NO.Cl |
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