RITA (NSC 652287)

目录号: A11931

p53 activator

RITA (NSC 652287)

RITA (NSC 652287) Chemical Structure

CAS NO. 213261-59-7

RITA,也称为NSC 652287,是一种三环噻吩衍生物,与MDM2结合,破坏MDM2-p53复合物,随后激活p53,并诱导凋亡。

库存: 现货

规格 价格 数量
5 mg
¥ 700.00
10 mg
¥ 1,200.00
25 mg
¥ 2,400.00
50 mg
¥ 4,000.00
10mM * 1mL in DMSO
¥ 1,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

RITA,也称为NSC 652287,是一种三环噻吩衍生物,与MDM2结合,破坏MDM2-p53复合物,随后激活p53,并诱导凋亡。
靶点信息
Mdm2 p53
In vitro (25°C) DMSO 56 mg/mL (191.53 mM)
Water Insoluble
Ethanol 8 mg/mL (27.36 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 34.2 mL 171 mL 342 mL
0.5 mM 6.84 mL 34.2 mL 68.4 mL
1 mM 3.42 mL 17.1 mL 34.2 mL
5 mM 0.68 mL 3.42 mL 6.84 mL

*The above data is based on the productmolecular weight 292.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11931
作用机制 Activator (激活剂)
M. Wt 292.4
Formula C14H12O3S2
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 213261-59-7
Synonyms NSC652287, p53 Activator III
SMILES C1=C(SC(=C1)C2=CC=C(O2)C3=CC=C(S3)CO)CO

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