Ritonavir

Name: Ritonavir
SKU: A10799

目录号: A10799

HIV Protease 抑制剂

Ritonavir Chemical Structure

CAS NO. 155213-67-5

Ritonavir是一种蛋白酶抑制剂，具有抗人类免疫缺陷病毒1型(hiv-1)的活性。蛋白酶抑制剂阻断hiv中被称为蛋白酶的部分，利托那韦抑制hiv病毒蛋白酶，这种蛋白酶防止gag-pol多蛋白的裂解，从而产生非感染性的未成熟病毒颗粒。

库存：现货

规格	价格	数量
10 mg	￥ 500.00
25 mg	￥ 800.00
50 mg	￥ 1,100.00
100 mg	￥ 1,500.00
10mM * 1mL in DMSO	￥ 500.00

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产品仅用于科学研究，不针对患者销售，望谅解.

产品详情

生物活性

靶点信息

CYP3A4	HIV

溶解度 *

In vitro (25°C)	DMSO	94 mg/mL (130.38 mM)
	Water	Insoluble
	Ethanol	3 mg/mL (4.16 mM)
In vivo	30% PEG400+0.5% Tween80+5% propylene glycol	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	13.87 mL	69.36 mL	138.72 mL
0.5 mM	2.77 mL	13.87 mL	27.74 mL
1 mM	1.39 mL	6.94 mL	13.87 mL
5 mM	0.28 mL	1.39 mL	2.77 mL

*The above data is based on the productmolecular weight 720.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10799
作用机制	Inhibitor (抑制剂)
M. Wt	720.9
Formula	C37H48N6O5S2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	155213-67-5
Synonyms	Norvir, Norvir Softgel
SMILES	CC(C)C1=NC(=CS1)CN(C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC2=CC=CC=C2)C[C@@H]([C@H](CC3=CC=CC=C3)NC(=O)OCC4=CN=CS4)O