Ro 31-8220

目录号: A21765

PKC inhibitor

Ro 31-8220

Ro 31-8220 Chemical Structure

CAS NO. 125314-64-9

Ro 31-8220 is a potent PKC inhibitor, with IC50s of 5, 24, 14, 27, 24 and 23 nM for PKCα, PKCβI, PKCβII, PKCγ, PKCε and rat brain PKC, respectively.

库存: 现货

规格 价格 数量
1 mg
¥ 3,200.00
5 mg
¥ 9,600.00
10 mg
¥ 16,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Ro 31-8220 is a potent PKC inhibitor, with IC50s of 5, 24, 14, 27, 24 and 23 nM for PKCα, PKCβI, PKCβII, PKCγ, PKCε and rat brain PKC, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.86 mL 109.28 mL 218.56 mL
0.5 mM 4.37 mL 21.86 mL 43.71 mL
1 mM 2.19 mL 10.93 mL 21.86 mL
5 mM 0.44 mL 2.19 mL 4.37 mL

*The above data is based on the productmolecular weight 457.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A21765
作用机制 Inhibitor (抑制剂)
M. Wt 457.55
Formula C25H23N5O2S
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 125314-64-9
Synonyms Bisindolylmaleimide IX, Ro31-8220, Ro-31-8220
SMILES NC(SCCCN1C=C(C2=C(C3=CN(C)C4=C3C=CC=C4)C(NC2=O)=O)C5=C1C=CC=C5)=N

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