ROR

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  1. SR-2211

    Catalog No. A13568
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    RORr 激动剂
    SR-2211选择性结合RORr(Ki = 105 nM),充当体外本构RORr活性的反向激动剂(IC50 = 320 nM)。 了解更多
  2. AGN-242428

    Catalog No. A16935
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    RORγt 抑制剂
    AGN-242428,也称为VTP-43742,是一种有效的,选择性的和口服活性的RORγ抑制剂,Ki值为<100 nM。用于治疗自身免疫性疾病,包括多发性硬化症和牛皮癣。 了解更多
  3. Cintirorgon (LYC-55716)

    Catalog No. A16863
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    RORγ 激动剂
    Cintirorgon (LYC-55716)是新型口服RAR相关孤儿受体γ(RORγ)激动剂。 了解更多
  4. AZD-0284

    Catalog No. A18766
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    RORγ 激动剂
    AZD-0284 is a potent, selective, inverse agonist of the nuclear receptor RORγ for the potential treatment of Plaque psoriasis. 了解更多
  5. XY101

    Catalog No. A18437
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    RORγ inverse 激动剂
    XY101 is a potent, selective, metabolically stable and orally available RORγ inverse agonist with an IC50 of 30 nM and a Kd of 380 nM. 了解更多
  6. S18-000003

    Catalog No. A19105
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    RORγt 抑制剂
    S18-000003 is a potent orally bioavailable retinoic acid receptor-related orphan receptor-gamma-t (RORγt) inhibitor with an IC50 of 29 nM. S18-000003 inhibits IL-17 production. 了解更多
  7. A-9758

    Catalog No. A19078
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    RORγt inverse 激动剂
    A-9758 is a RORγ ligand and a potent, selective RORγt inverse agonist (IC50=5 nM), and exhibits robust potency against IL-17A release. 了解更多
  8. ROR agonist-1

    Catalog No. A18569
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    ROR 激动剂
    ROR agonist-1 is a potent and orally bioavailable inverse agonist of the retinoic acid receptor-related orphan receptor C2 (RORC2), inhibition of IL-17A production from human primary TH 17 cells with a pIC50 of 7.5. 了解更多
  9. SR1078

    Catalog No. A15245
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    ROR 激动剂
    SR1078是视黄酸受体相关的孤儿受体(ROR)RORα/γ的激动剂;增加RORα靶基因的转录;认为可以增加p53的稳定性。 了解更多
  10. SR3335

    Catalog No. A15246
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    RORα 激动剂
    SR3335是一种选择性RORα合成配体,直接与RORα结合,但不与其他ROR结合,并且在基于细胞的测定中用作RORα的选择性部分反向激动剂。 了解更多
  11. SR1001

    Catalog No. A13193
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    ROR 激动剂
    SR1001是选择性的ROR-α和ROR-γ反向激动剂;抑制TH17细胞分化并抑制自身免疫。 了解更多
  12. ROR gamma modulator 1

    Catalog No. A16291
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    RORγ modulator
    ROR gamma modulator 1 是类维生素A相关的孤儿受体γ(RORy)调节剂 了解更多

12 个项目

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