Rosuvastatin calcium (Crestor)

Name: Rosuvastatin calcium (Crestor)
SKU: A10810

目录号: A10810

HMG-CoA reductase 抑制剂

Rosuvastatin calcium (Crestor) Chemical Structure

CAS NO. 147098-20-2

Rosuvastatin calcium (Crestor)是他汀类药物中的一员，用于治疗高胆固醇及相关疾病，并预防心血管疾病。罗苏伐他汀是一种竞争性HMG-CoA reductase抑制剂，无细胞试验中IC50为11 nM。

库存：现货

规格	价格	数量
25 mg	￥ 500.00
50 mg	￥ 700.00
100 mg	￥ 900.00
200 mg	￥ 1,200.00
10mM * 1mL in DMSO	￥ 550.00

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产品详情

溶解度 *

In vitro (25°C)	DMSO	Warmed: 91 mg/mL (181.79 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	4% DMSO+30% PEG 300+dd H2O	9 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.94 mL	99.7 mL	199.4 mL
0.5 mM	3.99 mL	19.94 mL	39.88 mL
1 mM	1.99 mL	9.97 mL	19.94 mL
5 mM	0.4 mL	1.99 mL	3.99 mL

*The above data is based on the productmolecular weight 501.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10810
作用机制	Inhibitor (抑制剂)
M. Wt	501.5
Formula	C22H28FN3O6S.1/2Ca
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	147098-20-2
SMILES	CC(C1=NC(=NC(=C1/C=C/[C@@H](O)C[C@@H](O)CC(=O)[O-])C2=CC=C(C=C2)F)N(S(=O)(=O)C)C)C.CC(C1=NC(=NC(=C1/C=C/[C@@H](O)C[C@@H](O)CC(=O)[O-])C2=CC=C(C=C2)F)N(S(=O)(=O)C)C)C.[Ca+2]