SAR245409 (XL765, Voxtalisib)

目录号: A16276

PI3K/mTOR dual 抑制剂

SAR245409 (XL765, Voxtalisib)

SAR245409 (XL765, Voxtalisib) Chemical Structure

CAS NO. 934493-76-2

SAR245409 (XL765,Voxtalisib)是PI3K/mTOR双激酶抑制剂XL765是口服生物可利用的小分子,靶向PI3K/mTOR信号途径中的磷脂酰肌醇3激酶(PI3K)和雷帕霉素(mTOR)激酶的哺乳动物靶标,具有潜在的抗肿瘤活性。

库存: 现货

规格 价格 数量
5 mg
¥ 800.00
10 mg
¥ 1,400.00
50 mg
¥ 4,150.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

SAR245409 (XL765,Voxtalisib)是PI3K/mTOR双激酶抑制剂XL765是口服生物可利用的小分子,靶向PI3K/mTOR信号途径中的磷脂酰肌醇3激酶(PI3K)和雷帕霉素(mTOR)激酶的哺乳动物靶标,具有潜在的抗肿瘤活性。
Targets
Target Value
PI3KγIC50: 9nM
PI3KαIC50: 39nM
PI3KδIC50: 43nM
PI3KβIC50: 113nM
DNA-PKIC50: 150nM
mTORIC50: 157nM
In vitro DMSO 53 mg/mL (196.08 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 37 mL 184.99 mL 369.97 mL
0.5 mM 7.4 mL 37 mL 73.99 mL
1 mM 3.7 mL 18.5 mL 37 mL
5 mM 0.74 mL 3.7 mL 7.4 mL

*The above data is based on the productmolecular weight 270.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A16276
作用机制 Inhibitor (抑制剂)
M. Wt 270.29
Formula C13H14N6O
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 934493-76-2
Synonyms Voxtalisib, XL765, SAR 245409, SAR-245409, XL 765, XL-765
SMILES O=C1C(C2=NNC=C2)=CC3=C(C)N=C(N)N=C3N1CC

产品标签

产品标签

使用空格分隔标签。使用单引号(')标注词组。

Product Questions

Product Questions

No Questions
Keywords:购买 SAR245409 (XL765, Voxtalisib) | SAR245409 (XL765, Voxtalisib) 供应商 | 订购 SAR245409 (XL765, Voxtalisib) | SAR245409 (XL765, Voxtalisib) 价格 | SAR245409 (XL765, Voxtalisib) 生产商 | 订单 SAR245409 (XL765, Voxtalisib) | SAR245409 (XL765, Voxtalisib) 代理商 | 购买 934493-76-2| 934493-76-2 供应商 | 订购 934493-76-2 | 934493-76-2 价格 | 934493-76-2 生产商 | 订单 934493-76-2 | 934493-76-2 代理商|buy SAR245409 (XL765, Voxtalisib) | SAR245409 (XL765, Voxtalisib) Supplier | purchase SAR245409 (XL765, Voxtalisib) | SAR245409 (XL765, Voxtalisib) cost | SAR245409 (XL765, Voxtalisib) manufacturer | order SAR245409 (XL765, Voxtalisib) | SAR245409 (XL765, Voxtalisib) distributor | buy 934493-76-2| 934493-76-2 Supplier | purchase 934493-76-2 | 934493-76-2 cost | 934493-76-2 manufacturer | order 934493-76-2 | 934493-76-2 distributor
Rewards