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SB 399885 hydrochloride是一种有效的，脑渗透剂和口服活性的SR-6拮抗剂。它对SR-6的选择性比其他血清素受体高200倍（对于人类重组，天然大鼠和天然人类SR-6受体，pKi值分别为9.11、8.81和9.02）。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.4 mL | 112.02 mL | 224.04 mL |
| 0.5 mM | 4.48 mL | 22.4 mL | 44.81 mL |
| 1 mM | 2.24 mL | 11.2 mL | 22.4 mL |
| 5 mM | 0.45 mL | 2.24 mL | 4.48 mL |
*The above data is based on the productmolecular weight 446.353. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A14102 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 446.353 |
| Formula | C18H21Cl2N3O4S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 402713-80-8 |
| Synonyms | SB399885, SB-399885 |
| SMILES | COC1=C(C=C(C=C1)S(=O)(=O)NC2=CC(=CC(=C2OC)Cl)Cl)N3CCNCC3.Cl |
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